2y9z
From Proteopedia
(Difference between revisions)
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<StructureSection load='2y9z' size='340' side='right' caption='[[2y9z]], [[Resolution|resolution]] 3.60Å' scene=''> | <StructureSection load='2y9z' size='340' side='right' caption='[[2y9z]], [[Resolution|resolution]] 3.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2y9z]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y9Z OCA]. <br> | + | <table><tr><td colspan='2'>[[2y9z]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y9Z FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y9y|2y9y]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y9y|2y9y]]</td></tr> |
| - | <tr | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y9z RCSB], [http://www.ebi.ac.uk/pdbsum/2y9z PDBsum]</span></td></tr> |
| - | + | </table> | |
| - | <table> | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/ISW1_YEAST ISW1_YEAST]] Catalytic component of ISW1-type complexes, which act by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. They are involved in coordinating transcriptional repression, activation and elongation phases. The ISW1A complex represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome. The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing.<ref>PMID:10090725</ref> <ref>PMID:11238381</ref> <ref>PMID:14622597</ref> <ref>PMID:12482963</ref> [[http://www.uniprot.org/uniprot/IOC3_YEAST IOC3_YEAST]] Functions as component of the ISW1A complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1A complex represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome.<ref>PMID:14622597</ref> <ref>PMID:12482963</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Structure and mechanism of the chromatin remodelling factor ISW1a.,Yamada K, Frouws TD, Angst B, Fitzgerald DJ, DeLuca C, Schimmele K, Sargent DF, Richmond TJ Nature. 2011 Apr 28;472(7344):448-53. PMID:21525927<ref>PMID:21525927</ref> | Structure and mechanism of the chromatin remodelling factor ISW1a.,Yamada K, Frouws TD, Angst B, Fitzgerald DJ, DeLuca C, Schimmele K, Sargent DF, Richmond TJ Nature. 2011 Apr 28;472(7344):448-53. PMID:21525927<ref>PMID:21525927</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Angst, B | + | [[Category: Angst, B]] |
| - | [[Category: Deluca, C | + | [[Category: Deluca, C]] |
| - | [[Category: Fitzgerald, D J | + | [[Category: Fitzgerald, D J]] |
| - | [[Category: Frouws, T D | + | [[Category: Frouws, T D]] |
| - | [[Category: Richmond, T J | + | [[Category: Richmond, T J]] |
| - | [[Category: Sargent, D F | + | [[Category: Sargent, D F]] |
| - | [[Category: Schimmele, K | + | [[Category: Schimmele, K]] |
| - | [[Category: Yamada, K | + | [[Category: Yamada, K]] |
[[Category: Chromatin remodeling]] | [[Category: Chromatin remodeling]] | ||
[[Category: Nuclear protein-dna complex]] | [[Category: Nuclear protein-dna complex]] | ||
[[Category: Nucleosome remodeling]] | [[Category: Nucleosome remodeling]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
Revision as of 10:31, 25 December 2014
Chromatin Remodeling Factor ISW1a(del_ATPase) in DNA complex
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