2y3r

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<StructureSection load='2y3r' size='340' side='right' caption='[[2y3r]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='2y3r' size='340' side='right' caption='[[2y3r]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y3r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._307-9 Streptomyces sp. 307-9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3R OCA]. <br>
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<table><tr><td colspan='2'>[[2y3r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_sp._307-9 Streptomyces sp. 307-9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3R FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TIR:TIRANDAMYCIN+E'>TIR</scene>, <scene name='pdbligand=TRK:TIRANDAMYCIN+D'>TRK</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TIR:TIRANDAMYCIN+E'>TIR</scene>, <scene name='pdbligand=TRK:TIRANDAMYCIN+D'>TRK</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y4g|2y4g]], [[2y08|2y08]], [[2y3s|2y3s]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y4g|2y4g]], [[2y08|2y08]], [[2y3s|2y3s]]</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3r RCSB], [http://www.ebi.ac.uk/pdbsum/2y3r PDBsum]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3r RCSB], [http://www.ebi.ac.uk/pdbsum/2y3r PDBsum]</span></td></tr>
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</table>
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<table>
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<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes.,Carlson JC, Li S, Gunatilleke SS, Anzai Y, Burr DA, Podust LM, Sherman DH Nat Chem. 2011 Jul 17;3(8):628-33. doi: 10.1038/nchem.1087. PMID:21778983<ref>PMID:21778983</ref>
Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes.,Carlson JC, Li S, Gunatilleke SS, Anzai Y, Burr DA, Podust LM, Sherman DH Nat Chem. 2011 Jul 17;3(8):628-33. doi: 10.1038/nchem.1087. PMID:21778983<ref>PMID:21778983</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Streptomyces sp. 307-9]]
[[Category: Streptomyces sp. 307-9]]
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[[Category: Anzai, Y.]]
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[[Category: Anzai, Y]]
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[[Category: Burr, D A.]]
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[[Category: Burr, D A]]
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[[Category: Carlson, J C.]]
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[[Category: Carlson, J C]]
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[[Category: Gunatilleke, S S.]]
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[[Category: Gunatilleke, S S]]
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[[Category: Li, S.]]
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[[Category: Li, S]]
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[[Category: Podust, L M.]]
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[[Category: Podust, L M]]
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[[Category: Sherman, D H.]]
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[[Category: Sherman, D H]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 22:18, 3 January 2015

STRUCTURE OF THE TIRANDAMYCIN-BOUND FAD-DEPENDENT TIRANDAMYCIN OXIDASE TAML IN P21 SPACE GROUP

2y3r, resolution 1.79Å

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