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2ycn
From Proteopedia
(Difference between revisions)
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<StructureSection load='2ycn' size='340' side='right' caption='[[2ycn]], [[Resolution|resolution]] 2.04Å' scene=''> | <StructureSection load='2ycn' size='340' side='right' caption='[[2ycn]], [[Resolution|resolution]] 2.04Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ycn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YCN OCA]. <br> | + | <table><tr><td colspan='2'>[[2ycn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YCN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YCN FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=P61:(2E)-3-(3-FLUORO-4-HYDROXYPHENYL)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}PROPANOIC+ACID'>P61</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=P61:(2E)-3-(3-FLUORO-4-HYDROXYPHENYL)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}PROPANOIC+ACID'>P61</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ez1|2ez1]], [[2vlh|2vlh]], [[2tpl|2tpl]], [[2vlf|2vlf]], [[2ez2|2ez2]], [[1tpl|1tpl]], [[2yct|2yct]], [[2ycp|2ycp]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ez1|2ez1]], [[2vlh|2vlh]], [[2tpl|2tpl]], [[2vlf|2vlf]], [[2ez2|2ez2]], [[1tpl|1tpl]], [[2yct|2yct]], [[2ycp|2ycp]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine_phenol-lyase Tyrosine phenol-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.2 4.1.99.2] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ycn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ycn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ycn RCSB], [http://www.ebi.ac.uk/pdbsum/2ycn PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ycn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ycn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ycn RCSB], [http://www.ebi.ac.uk/pdbsum/2ycn PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Crystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C-C Bond Cleavage.,Milic D, Demidkina TV, Faleev NG, Phillips RS, Matkovic-Calogovic D, Antson AA J Am Chem Soc. 2011 Oct 19;133(41):16468-76. Epub 2011 Sep 27. PMID:21899319<ref>PMID:21899319</ref> | Crystallographic Snapshots of Tyrosine Phenol-lyase Show That Substrate Strain Plays a Role in C-C Bond Cleavage.,Milic D, Demidkina TV, Faleev NG, Phillips RS, Matkovic-Calogovic D, Antson AA J Am Chem Soc. 2011 Oct 19;133(41):16468-76. Epub 2011 Sep 27. PMID:21899319<ref>PMID:21899319</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Citrobacter freundii]] | [[Category: Citrobacter freundii]] | ||
[[Category: Tyrosine phenol-lyase]] | [[Category: Tyrosine phenol-lyase]] | ||
| - | [[Category: Antson, A A | + | [[Category: Antson, A A]] |
| - | [[Category: Demidkina, T V | + | [[Category: Demidkina, T V]] |
| - | [[Category: Faleev, N G | + | [[Category: Faleev, N G]] |
| - | [[Category: Matkovic-Calogovic, D | + | [[Category: Matkovic-Calogovic, D]] |
| - | [[Category: Milic, D | + | [[Category: Milic, D]] |
| - | [[Category: Phillips, R S | + | [[Category: Phillips, R S]] |
[[Category: Beta-elimination]] | [[Category: Beta-elimination]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Pyridoxal 5'-phosphate dependent enzyme]] | [[Category: Pyridoxal 5'-phosphate dependent enzyme]] | ||
Revision as of 21:37, 3 January 2015
Y71F MUTANT OF TYROSINE PHENOL-LYASE FROM CITROBACTER FREUNDII IN COMPLEX WITH QUINONOID INTERMEDIATE FORMED WITH 3-FLUORO-L-TYROSINE
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