3axa

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3axa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AXA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3axa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AXA FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mllt4, Af6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mllt4, Af6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3axa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3axa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3axa RCSB], [http://www.ebi.ac.uk/pdbsum/3axa PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3axa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3axa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3axa RCSB], [http://www.ebi.ac.uk/pdbsum/3axa PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/AFAD_MOUSE AFAD_MOUSE]] Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm.<ref>PMID:10477764</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
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[[Category: Fujiwara, Y.]]
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[[Category: Fujiwara, Y]]
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[[Category: Goda, N.]]
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[[Category: Goda, N]]
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[[Category: Hiroaki, H.]]
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[[Category: Hiroaki, H]]
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[[Category: Nakagawa, A.]]
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[[Category: Nakagawa, A]]
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[[Category: Narita, H.]]
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[[Category: Narita, H]]
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[[Category: Sakisaka, T.]]
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[[Category: Sakisaka, T]]
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[[Category: Satomura, K.]]
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[[Category: Satomura, K]]
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[[Category: Suzuki, M.]]
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[[Category: Suzuki, M]]
[[Category: Af-6]]
[[Category: Af-6]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]
[[Category: Fusion protein]]
[[Category: Fusion protein]]
[[Category: Pdz domain]]
[[Category: Pdz domain]]

Revision as of 20:09, 25 December 2014

Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3

3axa, resolution 2.78Å

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