3axa
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3axa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AXA FirstGlance]. <br> | <table><tr><td colspan='2'>[[3axa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AXA FirstGlance]. <br> | ||
- | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mllt4, Af6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Mllt4, Af6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
- | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3axa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3axa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3axa RCSB], [http://www.ebi.ac.uk/pdbsum/3axa PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3axa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3axa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3axa RCSB], [http://www.ebi.ac.uk/pdbsum/3axa PDBsum]</span></td></tr> |
- | <table> | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/AFAD_MOUSE AFAD_MOUSE]] Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton. May play a key role in the organization of epithelial structures of the embryonic ectoderm.<ref>PMID:10477764</ref> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
- | [[Category: Fujiwara, Y | + | [[Category: Fujiwara, Y]] |
- | [[Category: Goda, N | + | [[Category: Goda, N]] |
- | [[Category: Hiroaki, H | + | [[Category: Hiroaki, H]] |
- | [[Category: Nakagawa, A | + | [[Category: Nakagawa, A]] |
- | [[Category: Narita, H | + | [[Category: Narita, H]] |
- | [[Category: Sakisaka, T | + | [[Category: Sakisaka, T]] |
- | [[Category: Satomura, K | + | [[Category: Satomura, K]] |
- | [[Category: Suzuki, M | + | [[Category: Suzuki, M]] |
[[Category: Af-6]] | [[Category: Af-6]] | ||
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Fusion protein]] | [[Category: Fusion protein]] | ||
[[Category: Pdz domain]] | [[Category: Pdz domain]] |
Revision as of 20:09, 25 December 2014
Crystal structure of afadin PDZ domain in complex with the C-terminal peptide from nectin-3
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Categories: Lk3 transgenic mice | Fujiwara, Y | Goda, N | Hiroaki, H | Nakagawa, A | Narita, H | Sakisaka, T | Satomura, K | Suzuki, M | Af-6 | Cell adhesion | Fusion protein | Pdz domain