This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lwh
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3lwh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LWH FirstGlance]. <br> | <table><tr><td colspan='2'>[[3lwh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LWH FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lwi|3lwi]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lwi|3lwi]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">creN7, SSO6901 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 SULSO])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">creN7, SSO6901 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 SULSO])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lwh RCSB], [http://www.ebi.ac.uk/pdbsum/3lwh PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lwh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lwh RCSB], [http://www.ebi.ac.uk/pdbsum/3lwh PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CREN7_SULSO CREN7_SULSO]] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 25: | ||
Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA.,Zhang Z, Gong Y, Guo L, Jiang T, Huang L Mol Microbiol. 2010 May;76(3):749-59. Epub 2010 Mar 16. PMID:20345658<ref>PMID:20345658</ref> | Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA.,Zhang Z, Gong Y, Guo L, Jiang T, Huang L Mol Microbiol. 2010 May;76(3):749-59. Epub 2010 Mar 16. PMID:20345658<ref>PMID:20345658</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
| Line 30: | Line 32: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Sulso]] | [[Category: Sulso]] | ||
| - | [[Category: Gong, Y | + | [[Category: Gong, Y]] |
| - | [[Category: Guo, L | + | [[Category: Guo, L]] |
| - | [[Category: Huang, L | + | [[Category: Huang, L]] |
| - | [[Category: Jiang, T | + | [[Category: Jiang, T]] |
| - | [[Category: Zhang, Z F | + | [[Category: Zhang, Z F]] |
[[Category: Beta-sheet]] | [[Category: Beta-sheet]] | ||
[[Category: Dna binding protein-dna complex]] | [[Category: Dna binding protein-dna complex]] | ||
Revision as of 09:22, 25 December 2014
Crystal structure of Cren7-dsDNA complex
| |||||||||||
