3lwi

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3lwi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LWI FirstGlance]. <br>
<table><tr><td colspan='2'>[[3lwi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulso Sulso]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LWI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lwh|3lwh]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lwh|3lwh]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">creN7, SSO6901 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 SULSO])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">creN7, SSO6901 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273057 SULSO])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lwi RCSB], [http://www.ebi.ac.uk/pdbsum/3lwi PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lwi RCSB], [http://www.ebi.ac.uk/pdbsum/3lwi PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CREN7_SULSO CREN7_SULSO]] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA.,Zhang Z, Gong Y, Guo L, Jiang T, Huang L Mol Microbiol. 2010 May;76(3):749-59. Epub 2010 Mar 16. PMID:20345658<ref>PMID:20345658</ref>
Structural insights into the interaction of the crenarchaeal chromatin protein Cren7 with DNA.,Zhang Z, Gong Y, Guo L, Jiang T, Huang L Mol Microbiol. 2010 May;76(3):749-59. Epub 2010 Mar 16. PMID:20345658<ref>PMID:20345658</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Sulso]]
[[Category: Sulso]]
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[[Category: Gong, Y.]]
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[[Category: Gong, Y]]
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[[Category: Guo, L.]]
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[[Category: Guo, L]]
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[[Category: Huang, L.]]
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[[Category: Huang, L]]
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[[Category: Jiang, T.]]
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[[Category: Jiang, T]]
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[[Category: Zhang, Z F.]]
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[[Category: Zhang, Z F]]
[[Category: Beta-sheet]]
[[Category: Beta-sheet]]
[[Category: Dna binding protein-dna complex]]
[[Category: Dna binding protein-dna complex]]

Revision as of 05:11, 25 December 2014

Crystal structure of Cren7-dsDNA complex

3lwi, resolution 2.30Å

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