1a79
From Proteopedia
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|PDB= 1a79 |SIZE=350|CAPTION= <scene name='initialview01'>1a79</scene>, resolution 2.28Å | |PDB= 1a79 |SIZE=350|CAPTION= <scene name='initialview01'>1a79</scene>, resolution 2.28Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=AU:GOLD+ION'>AU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a79 OCA], [http://www.ebi.ac.uk/pdbsum/1a79 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a79 RCSB]</span> | ||
}} | }} | ||
| Line 25: | Line 28: | ||
[[Category: Li, H.]] | [[Category: Li, H.]] | ||
[[Category: Trotta, C R.]] | [[Category: Trotta, C R.]] | ||
| - | [[Category: AU]] | ||
| - | [[Category: SO4]] | ||
[[Category: endonuclease]] | [[Category: endonuclease]] | ||
[[Category: trna endonuclease]] | [[Category: trna endonuclease]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:34:46 2008'' |
Revision as of 15:34, 30 March 2008
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| , resolution 2.28Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
CRYSTAL STRUCTURE OF THE TRNA SPLICING ENDONUCLEASE FROM METHANOCOCCUS JANNASCHII
Overview
The splicing of transfer RNA precursors is similar in Eucarya and Archaea. In both kingdoms an endonuclease recognizes the splice sites and releases the intron, but the mechanism of splice site recognition is different in each kingdom. The crystal structure of the endonuclease from the archaeon Methanococcus jannaschii was determined to a resolution of 2.3 angstroms. The structure indicates that the cleavage reaction is similar to that of ribonuclease A and the arrangement of the active sites is conserved between the archaeal and eucaryal enzymes. These results suggest an evolutionary pathway for splice site recognition.
About this Structure
1A79 is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.
Reference
Crystal structure and evolution of a transfer RNA splicing enzyme., Li H, Trotta CR, Abelson J, Science. 1998 Apr 10;280(5361):279-84. PMID:9535656
Page seeded by OCA on Sun Mar 30 18:34:46 2008
