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2xc1
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xc1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpp22 Bpp22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XC1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2xc1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpp22 Bpp22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XC1 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vfo|2vfo]], [[2vky|2vky]], [[2vfn|2vfn]], [[1tyu|1tyu]], [[1qrc|1qrc]], [[2vfq|2vfq]], [[1clw|1clw]], [[1tyw|1tyw]], [[2vnl|2vnl]], [[1tyx|1tyx]], [[1qrb|1qrb]], [[1tsp|1tsp]], [[1qa2|1qa2]], [[2vfp|2vfp]], [[2vfm|2vfm]], [[1lkt|1lkt]], [[1qa3|1qa3]], [[1qa1|1qa1]], [[1tyv|1tyv]], [[1qq1|1qq1]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vfo|2vfo]], [[2vky|2vky]], [[2vfn|2vfn]], [[1tyu|1tyu]], [[1qrc|1qrc]], [[2vfq|2vfq]], [[1clw|1clw]], [[1tyw|1tyw]], [[2vnl|2vnl]], [[1tyx|1tyx]], [[1qrb|1qrb]], [[1tsp|1tsp]], [[1qa2|1qa2]], [[2vfp|2vfp]], [[2vfm|2vfm]], [[1lkt|1lkt]], [[1qa3|1qa3]], [[1qa1|1qa1]], [[1tyv|1tyv]], [[1qq1|1qq1]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xc1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xc1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xc1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xc1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xc1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xc1 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TSPE_BPP22 TSPE_BPP22]] Non-covalently bound to the neck of the phage capsid and mediating attachment of the viral particle to host cell-surface polysaccharide. It displays endorhamnosidase enzymatic activity, hydrolyzing the alpha-1,3-O-glycosidic linkage between rhamnose and galactose of the O-antigen polysaccharide.<ref>PMID:12837775</ref> <ref>PMID:20817910</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker.,Seul A, Muller JJ, Andres D, Stettner E, Heinemann U, Seckler R Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1336-45. doi:, 10.1107/S1399004714002685. Epub 2014 Apr 30. PMID:24816102<ref>PMID:24816102</ref> | Bacteriophage P22 tailspike: structure of the complete protein and function of the interdomain linker.,Seul A, Muller JJ, Andres D, Stettner E, Heinemann U, Seckler R Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1336-45. doi:, 10.1107/S1399004714002685. Epub 2014 Apr 30. PMID:24816102<ref>PMID:24816102</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bpp22]] | [[Category: Bpp22]] | ||
| - | [[Category: Heinemann, U | + | [[Category: Heinemann, U]] |
| - | [[Category: Mueller, J J | + | [[Category: Mueller, J J]] |
| - | [[Category: Seckler, R | + | [[Category: Seckler, R]] |
| - | [[Category: Seul, A | + | [[Category: Seul, A]] |
[[Category: Endoglycosidase]] | [[Category: Endoglycosidase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Salmonella phage p22]] | [[Category: Salmonella phage p22]] | ||
Revision as of 08:28, 24 December 2014
Full-length Tailspike Protein Mutant Y108W of Bacteriophage P22
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