3rrd

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rrd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dioclea_virgata Dioclea virgata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RRD FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rrd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dioclea_virgata Dioclea virgata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RRD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RRD FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rrd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rrd RCSB], [http://www.ebi.ac.uk/pdbsum/3rrd PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rrd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rrd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rrd RCSB], [http://www.ebi.ac.uk/pdbsum/3rrd PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LECA_DIOVI LECA_DIOVI]] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from hamster and rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 20 ug/ml.[REFERENCE:1]<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:8891754</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structure of Dioclea virgata lectin: Relations between carbohydrate binding site and nitric oxide production.,Batista da Nobrega R, Rocha BA, Gadelha CA, Santi-Gadelha T, Pires AF, Assreuy AM, Nascimento KS, Nagano CS, Sampaio AH, Cavada BS, Delatorre P Biochimie. 2011 Dec 16. PMID:22198239<ref>PMID:22198239</ref>
Structure of Dioclea virgata lectin: Relations between carbohydrate binding site and nitric oxide production.,Batista da Nobrega R, Rocha BA, Gadelha CA, Santi-Gadelha T, Pires AF, Assreuy AM, Nascimento KS, Nagano CS, Sampaio AH, Cavada BS, Delatorre P Biochimie. 2011 Dec 16. PMID:22198239<ref>PMID:22198239</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Dioclea virgata]]
[[Category: Dioclea virgata]]
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[[Category: Alencar, K L.]]
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[[Category: Alencar, K L]]
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[[Category: Bezerra, E H.S.]]
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[[Category: Bezerra, E H.S]]
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[[Category: Bezerra, M J.]]
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[[Category: Bezerra, M J]]
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[[Category: Cavada, B S.]]
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[[Category: Cavada, B S]]
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[[Category: Delatorre, P.]]
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[[Category: Delatorre, P]]
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[[Category: Farias, D L.]]
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[[Category: Farias, D L]]
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[[Category: Gadelha, C A.A.]]
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[[Category: Gadelha, C A.A]]
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[[Category: Nagano, C S.]]
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[[Category: Nagano, C S]]
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[[Category: Nobrega, R B.]]
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[[Category: Nobrega, R B]]
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[[Category: Rocha, B A.M.]]
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[[Category: Rocha, B A.M]]
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[[Category: Santi-Gadelha, T.]]
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[[Category: Santi-Gadelha, T]]
[[Category: Carbohydrate binding protein]]
[[Category: Carbohydrate binding protein]]
[[Category: Cona-like lectin]]
[[Category: Cona-like lectin]]

Revision as of 05:42, 25 December 2014

Native structure of Dioclea virgata lectin

3rrd, resolution 2.46Å

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