3dwr
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3dwr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DWR FirstGlance]. <br> | <table><tr><td colspan='2'>[[3dwr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DWR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DWR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PA:CYCLOPENTYLACETIC+ACID'>0PA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0PA:CYCLOPENTYLACETIC+ACID'>0PA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qt8|2qt8]], [[1vju|1vju]], [[3dws|3dws]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qt8|2qt8]], [[1vju|1vju]], [[3dws|3dws]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMAJ006828, LmjF06.1270 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 Leishmania major])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMAJ006828, LmjF06.1270 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5664 Leishmania major])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coproporphyrinogen_oxidase Coproporphyrinogen oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.3 1.3.3.3] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dwr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dwr RCSB], [http://www.ebi.ac.uk/pdbsum/3dwr PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dwr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dwr RCSB], [http://www.ebi.ac.uk/pdbsum/3dwr PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HEM6_LEIMA HEM6_LEIMA]] Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).[HAMAP-Rule:MF_00333] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 25: | ||
[[Category: Coproporphyrinogen oxidase]] | [[Category: Coproporphyrinogen oxidase]] | ||
[[Category: Leishmania major]] | [[Category: Leishmania major]] | ||
| - | [[Category: Merritt, E A | + | [[Category: Merritt, E A]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Trong, I Le | + | [[Category: Trong, I Le]] |
[[Category: Fragment cocktail]] | [[Category: Fragment cocktail]] | ||
[[Category: Heme biosynthesis]] | [[Category: Heme biosynthesis]] | ||
| Line 31: | Line 33: | ||
[[Category: Porphyrin biosynthesis]] | [[Category: Porphyrin biosynthesis]] | ||
[[Category: Sgpp]] | [[Category: Sgpp]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics of pathogenic protozoa consortium]] | ||
Revision as of 00:12, 25 December 2014
Leishmania major coproporphyrinogen III oxidase with bound ligand
| |||||||||||
