3hn8

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hn8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HN8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hn8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HN8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Syt3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Syt3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hn8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hn8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hn8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hn8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hn8 RCSB], [http://www.ebi.ac.uk/pdbsum/3hn8 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SYT3_RAT SYT3_RAT]] May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.,Vrljic M, Strop P, Ernst JA, Sutton RB, Chu S, Brunger AT Nat Struct Mol Biol. 2010 Mar;17(3):325-31. Epub 2010 Feb 21. PMID:20173762<ref>PMID:20173762</ref>
Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion.,Vrljic M, Strop P, Ernst JA, Sutton RB, Chu S, Brunger AT Nat Struct Mol Biol. 2010 Mar;17(3):325-31. Epub 2010 Feb 21. PMID:20173762<ref>PMID:20173762</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Brunger, A T.]]
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[[Category: Brunger, A T]]
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[[Category: Ernst, J.]]
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[[Category: Ernst, J]]
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[[Category: Strop, P.]]
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[[Category: Strop, P]]
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[[Category: Vrljic, M.]]
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[[Category: Vrljic, M]]
[[Category: Cell junction]]
[[Category: Cell junction]]
[[Category: Cytoplasmic vesicle]]
[[Category: Cytoplasmic vesicle]]

Revision as of 10:55, 25 December 2014

Crystal structure of synaptotagmin

3hn8, resolution 3.50Å

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