3fb1
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3fb1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FB1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FB1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3fb1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FB1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FB1 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=R1P:RIBOSE-1-PHOSPHATE'>R1P</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1td1|1td1]], [[1tcu|1tcu]], [[1tcv|1tcv]], [[3f8w|3f8w]], [[3faz|3faz]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1td1|1td1]], [[1tcu|1tcu]], [[1tcv|1tcv]], [[3f8w|3f8w]], [[3faz|3faz]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SmPNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Schistosoma mansoni])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SmPNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Schistosoma mansoni])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fb1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fb1 RCSB], [http://www.ebi.ac.uk/pdbsum/3fb1 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fb1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fb1 RCSB], [http://www.ebi.ac.uk/pdbsum/3fb1 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q9BMI9_SCHMA Q9BMI9_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity).[PIRNR:PIRNR000477] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.,D'Muniz Pereira H, Oliva G, Garratt RC J Synchrotron Radiat. 2011 Jan;18(1):62-5. Epub 2010 Nov 12. PMID:21169694<ref>PMID:21169694</ref> | Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.,D'Muniz Pereira H, Oliva G, Garratt RC J Synchrotron Radiat. 2011 Jan;18(1):62-5. Epub 2010 Nov 12. PMID:21169694<ref>PMID:21169694</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Purine nucleoside phosphorylase|Purine nucleoside phosphorylase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Purine-nucleoside phosphorylase]] | [[Category: Purine-nucleoside phosphorylase]] | ||
[[Category: Schistosoma mansoni]] | [[Category: Schistosoma mansoni]] | ||
| - | [[Category: Garratt, R C | + | [[Category: Garratt, R C]] |
| - | [[Category: Oliva, G | + | [[Category: Oliva, G]] |
| - | [[Category: Pereira, H M | + | [[Category: Pereira, H M]] |
[[Category: Glycosyltransferase]] | [[Category: Glycosyltransferase]] | ||
[[Category: Purine nucleoside phsophorylase]] | [[Category: Purine nucleoside phsophorylase]] | ||
[[Category: Ribose-1-phosphate]] | [[Category: Ribose-1-phosphate]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 19:26, 24 December 2014
Crystal Structure of Purine Nucleoside Phosphorylase in Complex with Ribose-1-Phosphate
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