3g7d

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3g7d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_viridochromogenes Streptomyces viridochromogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G7D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G7D FirstGlance]. <br>
<table><tr><td colspan='2'>[[3g7d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_viridochromogenes Streptomyces viridochromogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G7D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G7D FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Phosphinothricin biosynthetic cluster, phpD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1938 Streptomyces viridochromogenes])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Phosphinothricin biosynthetic cluster, phpD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1938 Streptomyces viridochromogenes])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g7d RCSB], [http://www.ebi.ac.uk/pdbsum/3g7d PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g7d RCSB], [http://www.ebi.ac.uk/pdbsum/3g7d PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/Q5IW40_STRVR Q5IW40_STRVR]] Non-heme-dependent dioxygenase that catalyzes the conversion of 2-hydroxyethylphosphonate (HEP) to hydroxymethylphosphonate (HMP) in the biosynthesis of phosphinothricin tripeptide (PTT). PTT contains the unusual amino acid phosphinothricin attached to 2 alanine residues. Synthetic phosphinothricin (glufosinate) is a key component of commercial herbicides.<ref>PMID:17632514</ref> <ref>PMID:19839620</ref> <ref>PMID:21381767</ref> <ref>PMID:19516340</ref> <ref>PMID:21711001</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis.,Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW Nature. 2009 Jun 11;459(7248):871-4. PMID:19516340<ref>PMID:19516340</ref>
An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis.,Cicchillo RM, Zhang H, Blodgett JA, Whitteck JT, Li G, Nair SK, van der Donk WA, Metcalf WW Nature. 2009 Jun 11;459(7248):871-4. PMID:19516340<ref>PMID:19516340</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Streptomyces viridochromogenes]]
[[Category: Streptomyces viridochromogenes]]
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[[Category: Nair, S K.]]
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[[Category: Nair, S K]]
[[Category: Biosynthetic protein]]
[[Category: Biosynthetic protein]]
[[Category: Cupin]]
[[Category: Cupin]]

Revision as of 18:07, 25 December 2014

Native PhpD with Cadmium Atoms

3g7d, resolution 1.80Å

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