3ew0
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3ew0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EW0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EW0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3ew0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EW0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EW0 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qh7|2qh7]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qh7|2qh7]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C10orf70, CISD1, MDS029, ZCD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C10orf70, CISD1, MDS029, ZCD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ew0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ew0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ew0 RCSB], [http://www.ebi.ac.uk/pdbsum/3ew0 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ew0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ew0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ew0 RCSB], [http://www.ebi.ac.uk/pdbsum/3ew0 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CISD1_HUMAN CISD1_HUMAN]] Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions.<ref>PMID:17584744</ref> <ref>PMID:17766440</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain.,Conlan AR, Paddock ML, Axelrod HL, Cohen AE, Abresch EC, Wiley S, Roy M, Nechushtai R, Jennings PA Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt 7):654-9. Epub, 2009 Jun 27. PMID:19574633<ref>PMID:19574633</ref> | The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain.,Conlan AR, Paddock ML, Axelrod HL, Cohen AE, Abresch EC, Wiley S, Roy M, Nechushtai R, Jennings PA Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt 7):654-9. Epub, 2009 Jun 27. PMID:19574633<ref>PMID:19574633</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Abresch, E C | + | [[Category: Abresch, E C]] |
| - | [[Category: Axelrod, H L | + | [[Category: Axelrod, H L]] |
| - | [[Category: Cohen, A E | + | [[Category: Cohen, A E]] |
| - | [[Category: Conlan, A R | + | [[Category: Conlan, A R]] |
| - | [[Category: Jennings, P A | + | [[Category: Jennings, P A]] |
| - | [[Category: Nechushtai, R | + | [[Category: Nechushtai, R]] |
| - | [[Category: Paddock, M L | + | [[Category: Paddock, M L]] |
[[Category: Roy, Melinda]] | [[Category: Roy, Melinda]] | ||
| - | [[Category: Wiley, S | + | [[Category: Wiley, S]] |
[[Category: 2fe-2s protein]] | [[Category: 2fe-2s protein]] | ||
[[Category: Highyield expression]] | [[Category: Highyield expression]] | ||
Revision as of 19:49, 25 December 2014
The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain
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Categories: Homo sapiens | Abresch, E C | Axelrod, H L | Cohen, A E | Conlan, A R | Jennings, P A | Nechushtai, R | Paddock, M L | Roy, Melinda | Wiley, S | 2fe-2s protein | Highyield expression | Iron | Iron-sulfur | Isotopic labeling | Membrane | Metal binding protein | Metal-binding | Mitochondrial outer membrane | Mitochondrion | Mitochondrion outer membrane | Signal-anchor | Transmembrane
