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| - | ==Model of the large subunit RNA based on a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome (with ES27L-in conformation)==
| + | #REDIRECT [[4v6i]] This PDB entry is obsolete and replaced by 4v6i |
| - | <StructureSection load='3izf' size='340' side='right' caption='[[3izf]], [[Resolution|resolution]] 8.80Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[3izf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IZF FirstGlance]. <br>
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| - | </td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iz5|3iz5]], [[3iz6|3iz6]], [[3iz7|3iz7]], [[3iz9|3iz9]], [[3izb|3izb]], [[3izs|3izs]], [[3izd|3izd]], [[3ize|3ize]]</td></tr>
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| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3izf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3izf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3izf RCSB], [http://www.ebi.ac.uk/pdbsum/3izf PDBsum]</span></td></tr>
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| - | <table>
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| - | <div style="background-color:#fffaf0;">
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| - | == Publication Abstract from PubMed ==
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| - | Protein biosynthesis, the translation of the genetic code into polypeptides, occurs on ribonucleoprotein particles called ribosomes. Although X-ray structures of bacterial ribosomes are available, high-resolution structures of eukaryotic 80S ribosomes are lacking. Using cryoelectron microscopy and single-particle reconstruction, we have determined the structure of a translating plant (Triticum aestivum) 80S ribosome at 5.5-A resolution. This map, together with a 6.1-A map of a Saccharomyces cerevisiae 80S ribosome, has enabled us to model approximately 98% of the rRNA. Accurate assignment of the rRNA expansion segments (ES) and variable regions has revealed unique ES-ES and r-protein-ES interactions, providing insight into the structure and evolution of the eukaryotic ribosome.
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| - | Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.,Armache JP, Jarasch A, Anger AM, Villa E, Becker T, Bhushan S, Jossinet F, Habeck M, Dindar G, Franckenberg S, Marquez V, Mielke T, Thomm M, Berninghausen O, Beatrix B, Soding J, Westhof E, Wilson DN, Beckmann R Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19748-53. Epub 2010 Oct 27. PMID:20980660<ref>PMID:20980660</ref>
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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| - | </div>
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| - | == References ==
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| - | <references/>
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Saccharomyces cerevisiae]]
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| - | [[Category: Anger, A M.]]
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| - | [[Category: Armache, J P.]]
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| - | [[Category: Beatrix, B.]]
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| - | [[Category: Becker, T.]]
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| - | [[Category: Beckmann, R.]]
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| - | [[Category: Berninghausen, O.]]
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| - | [[Category: Bhushan, S.]]
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| - | [[Category: Dindar, G.]]
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| - | [[Category: Franckenberg, S.]]
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| - | [[Category: Habeck, M.]]
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| - | [[Category: Jarasch, A.]]
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| - | [[Category: Jossinet, F.]]
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| - | [[Category: Marquez, V.]]
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| - | [[Category: Mielke, T.]]
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| - | [[Category: Soeding, J.]]
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| - | [[Category: Thomm, M.]]
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| - | [[Category: Villa, E.]]
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| - | [[Category: Westhof, E.]]
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| - | [[Category: Wilson, D N.]]
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| - | [[Category: De novo modeling]]
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| - | [[Category: Eukaryotic ribosome]]
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| - | [[Category: Homology modelling]]
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| - | [[Category: Ribosomal rna]]
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| - | [[Category: Ribosome]]
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| - | [[Category: Rna expansion segment]]
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| - | [[Category: Rrna]]
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