3c3n
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3c3n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C3N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C3N FirstGlance]. <br> | <table><tr><td colspan='2'>[[3c3n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C3N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3C3N FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tcdhod2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 TRYCR])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tcdhod2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5693 TRYCR])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c3n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c3n RCSB], [http://www.ebi.ac.uk/pdbsum/3c3n PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c3n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c3n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3c3n RCSB], [http://www.ebi.ac.uk/pdbsum/3c3n PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/Q4D3W2_TRYCR Q4D3W2_TRYCR]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain.,Pinheiro MP, Iulek J, Cristina Nonato M Biochem Biophys Res Commun. 2008 May 9;369(3):812-7. Epub 2008 Feb 25. PMID:18302934<ref>PMID:18302934</ref> | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase from Y strain.,Pinheiro MP, Iulek J, Cristina Nonato M Biochem Biophys Res Commun. 2008 May 9;369(3):812-7. Epub 2008 Feb 25. PMID:18302934<ref>PMID:18302934</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 30: | Line 35: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Trycr]] | [[Category: Trycr]] | ||
| - | [[Category: Iulek, J | + | [[Category: Iulek, J]] |
| - | [[Category: Nonato, M C | + | [[Category: Nonato, M C]] |
| - | [[Category: Pinheiro, M P | + | [[Category: Pinheiro, M P]] |
[[Category: Dhodh]] | [[Category: Dhodh]] | ||
[[Category: Dihydroorotate dehydrogenase]] | [[Category: Dihydroorotate dehydrogenase]] | ||
Revision as of 08:44, 24 December 2014
Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y
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