3iyp
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br> | <table><tr><td colspan='2'>[[3iyp]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Human_echovirus_7 Human echovirus 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IYP FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DAO:LAURIC+ACID'>DAO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DAF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3iyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iyp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3iyp RCSB], [http://www.ebi.ac.uk/pdbsum/3iyp PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref> | The Interaction of Decay-accelerating Factor with Echovirus 7.,Plevka P, Hafenstein S, Harris KG, Cifuente JO, Zhang Y, Bowman VD, Chipman PR, Bator CM, Lin F, Medof ME, Rossmann MG J Virol. 2010 Sep 29. PMID:20881044<ref>PMID:20881044</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Human echovirus 7]] | [[Category: Human echovirus 7]] | ||
| - | [[Category: Bator, C M | + | [[Category: Bator, C M]] |
| - | [[Category: Bowman, V D | + | [[Category: Bowman, V D]] |
| - | [[Category: Chipman, P R | + | [[Category: Chipman, P R]] |
| - | [[Category: Cifuente, J O | + | [[Category: Cifuente, J O]] |
| - | [[Category: Hafenstein, S | + | [[Category: Hafenstein, S]] |
| - | [[Category: Harris, K G | + | [[Category: Harris, K G]] |
| - | [[Category: Lin, F | + | [[Category: Lin, F]] |
| - | [[Category: Medof, D E | + | [[Category: Medof, D E]] |
| - | [[Category: Plevka, P | + | [[Category: Plevka, P]] |
| - | [[Category: Rossmann, M G | + | [[Category: Rossmann, M G]] |
| - | [[Category: Zhang, Y | + | [[Category: Zhang, Y]] |
[[Category: Complex]] | [[Category: Complex]] | ||
[[Category: Daf]] | [[Category: Daf]] | ||
Revision as of 11:06, 25 December 2014
The Interaction of Decay-accelerating Factor with Echovirus 7
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Categories: Homo sapiens | Human echovirus 7 | Bator, C M | Bowman, V D | Chipman, P R | Cifuente, J O | Hafenstein, S | Harris, K G | Lin, F | Medof, D E | Plevka, P | Rossmann, M G | Zhang, Y | Complex | Daf | Echovirus | Icosahedral virus | Receptor | Virus
