Tumor necrosis factor
From Proteopedia
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'''Tumor necrosis factor''' (TNF) is a cytokine which can cause apoptosis. TNFα is implicated in tumor regression, septic shock, inflammation and cachexia (wasting syndrome). It is involved in the regulation of the immune cells. TNF is a transmembrane homotrimer. The soluble TNF is produced by cleavage by the metalloprotease TNF alpha converting enzyme (TACE or ADAM17 see [[A Disintegrin And Metalloproteinase]]). | '''Tumor necrosis factor''' (TNF) is a cytokine which can cause apoptosis. TNFα is implicated in tumor regression, septic shock, inflammation and cachexia (wasting syndrome). It is involved in the regulation of the immune cells. TNF is a transmembrane homotrimer. The soluble TNF is produced by cleavage by the metalloprotease TNF alpha converting enzyme (TACE or ADAM17 see [[A Disintegrin And Metalloproteinase]]). | ||
| + | </StructureSection> | ||
== 3D Structures of tumor necrosis factor == | == 3D Structures of tumor necrosis factor == | ||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | + | *TNF alpha | |
| - | [[1tnf]] – hTNF – human <BR /> | + | **[[1tnf]] – hTNF – human <BR /> |
| - | [[2tun]], [[1a8m]], [[4tsv]], [[5tsw]], [[2e7e]], [[2zjc]], [[2zpx]] – hTNF (mutant) <BR /> | + | **[[2tun]], [[1a8m]], [[4tsv]], [[5tsw]], [[2e7e]], [[2zjc]], [[2zpx]] – hTNF (mutant) <BR /> |
| - | [[2tnf]] – TNF – mouse <BR /> | + | **[[2tnf]] – TNF – mouse <BR /> |
| - | [[2az5]] – hTNF + inhibitor <BR /> | + | **[[2az5]] – hTNF + inhibitor <BR /> |
| - | [[3it8]] – hTNF + poxvirus 2L protein <BR /> | + | **[[3it8]] – hTNF + poxvirus 2L protein <BR /> |
| - | [[3l9j]] – hTNF + antagonist <BR /> | + | **[[3l9j]] – hTNF + antagonist <BR /> |
| - | [[3alq]] – hTNF (mutant) + TNF receptor <BR /> | + | **[[3alq]] – hTNF (mutant) + TNF receptor <BR /> |
| - | [[4g3y]], [[3wd5]] – hTNF + antibody <BR /> | + | **[[4g3y]], [[3wd5]] – hTNF + antibody <BR /> |
| - | + | *TNF beta | |
| - | [[1tnr]] – hTNF + TNF receptor p55 <BR /> | + | **[[1tnr]] – hTNF + TNF receptor p55 <BR /> |
| - | + | *TNF | |
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| + | **[[2vfj]] – hTNF ovarian tumor domain <BR /> | ||
| + | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 07:17, 16 December 2014
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3D Structures of tumor necrosis factor
Updated on 16-December-2014
