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4lcl
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4lcl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspte Aspte]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LCL FirstGlance]. <br> | <table><tr><td colspan='2'>[[4lcl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspte Aspte]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LCL FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hl9|3hl9]], [[3hlb|3hlb]], [[3hlc|3hlc]], [[3hld|3hld]], [[3hle|3hle]], [[3hlf|3hlf]], [[3hlg|3hlg]], [[4lcm|4lcm]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hl9|3hl9]], [[3hlb|3hlb]], [[3hlc|3hlc]], [[3hld|3hld]], [[3hle|3hle]], [[3hlf|3hlf]], [[3hlg|3hlg]], [[4lcm|4lcm]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lovD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33178 ASPTE])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lovD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33178 ASPTE])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lcl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lcl RCSB], [http://www.ebi.ac.uk/pdbsum/4lcl PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lcl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lcl RCSB], [http://www.ebi.ac.uk/pdbsum/4lcl PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The role of distant mutations and allosteric regulation on LovD active site dynamics.,Jimenez-Oses G, Osuna S, Gao X, Sawaya MR, Gilson L, Collier SJ, Huisman GW, Yeates TO, Tang Y, Houk KN Nat Chem Biol. 2014 Jun;10(6):431-6. doi: 10.1038/nchembio.1503. Epub 2014 Apr, 13. PMID:24727900<ref>PMID:24727900</ref> | The role of distant mutations and allosteric regulation on LovD active site dynamics.,Jimenez-Oses G, Osuna S, Gao X, Sawaya MR, Gilson L, Collier SJ, Huisman GW, Yeates TO, Tang Y, Houk KN Nat Chem Biol. 2014 Jun;10(6):431-6. doi: 10.1038/nchembio.1503. Epub 2014 Apr, 13. PMID:24727900<ref>PMID:24727900</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aspte]] | [[Category: Aspte]] | ||
| - | [[Category: Gao, X | + | [[Category: Gao, X]] |
| - | [[Category: Sawaya, M R | + | [[Category: Sawaya, M R]] |
| - | [[Category: Tang, Y | + | [[Category: Tang, Y]] |
| - | [[Category: Yeates, T O | + | [[Category: Yeates, T O]] |
[[Category: Laboratory-directed evolution]] | [[Category: Laboratory-directed evolution]] | ||
[[Category: Transesterase]] | [[Category: Transesterase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 09:12, 5 January 2015
Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD6 mutant (simh6208)
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