4pwn
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4pwn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PWN FirstGlance]. <br> | <table><tr><td colspan='2'>[[4pwn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PWN FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fpq|3fpq]], [[4q2a|4q2a]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fpq|3fpq]], [[4q2a|4q2a]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pwn RCSB], [http://www.ebi.ac.uk/pdbsum/4pwn PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pwn RCSB], [http://www.ebi.ac.uk/pdbsum/4pwn PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/WNK1_HUMAN WNK1_HUMAN]] Hereditary sensory and autonomic neuropathy type 2;Pseudohypoaldosteronism type 2C. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/WNK1_HUMAN WNK1_HUMAN]] Hereditary sensory and autonomic neuropathy type 2;Pseudohypoaldosteronism type 2C. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
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Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation.,Piala AT, Moon TM, Akella R, He H, Cobb MH, Goldsmith EJ Sci Signal. 2014 May 6;7(324):ra41. doi: 10.1126/scisignal.2005050. PMID:24803536<ref>PMID:24803536</ref> | Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation.,Piala AT, Moon TM, Akella R, He H, Cobb MH, Goldsmith EJ Sci Signal. 2014 May 6;7(324):ra41. doi: 10.1126/scisignal.2005050. PMID:24803536<ref>PMID:24803536</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Akella, T | + | [[Category: Akella, T]] |
| - | [[Category: Cobbm, M H | + | [[Category: Cobbm, M H]] |
| - | [[Category: Goldsmith, E | + | [[Category: Goldsmith, E]] |
| - | [[Category: He, H | + | [[Category: He, H]] |
| - | [[Category: Moon, T | + | [[Category: Moon, T]] |
| - | [[Category: Piala, A | + | [[Category: Piala, A]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
Revision as of 09:41, 5 January 2015
Crystal structure of Active WNK1 kinase
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