3nk0
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3nk0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_nicotinovorans Arthrobacter nicotinovorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK0 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3nk0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_nicotinovorans Arthrobacter nicotinovorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NK0 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GP7:(1R)-2-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTADECANOYLOXY)METHYL]ETHYL+(12E)-HEXADECA-9,12-DIENOATE'>GP7</scene>, <scene name='pdbligand=HNK:5-[(2R)-1-METHYLPYRROLIDIN-2-YL]PYRIDIN-2-OL'>HNK</scene>, <scene name='pdbligand=HNM:1-(6-HYDROXYPYRIDIN-3-YL)-4-(METHYLAMINO)BUTAN-1-ONE'>HNM</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GP7:(1R)-2-{[(S)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTADECANOYLOXY)METHYL]ETHYL+(12E)-HEXADECA-9,12-DIENOATE'>GP7</scene>, <scene name='pdbligand=HNK:5-[(2R)-1-METHYLPYRROLIDIN-2-YL]PYRIDIN-2-OL'>HNK</scene>, <scene name='pdbligand=HNM:1-(6-HYDROXYPYRIDIN-3-YL)-4-(METHYLAMINO)BUTAN-1-ONE'>HNM</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ngc|3ngc]], [[3nh3|3nh3]], [[3nho|3nho]], [[3nk1|3nk1]], [[3nk2|3nk2]], [[3nn0|3nn0]], [[3nn6|3nn6]], [[3k7m|3k7m]], [[3k7q|3k7q]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ngc|3ngc]], [[3nh3|3nh3]], [[3nho|3nho]], [[3nk1|3nk1]], [[3nk2|3nk2]], [[3nn0|3nn0]], [[3nn6|3nn6]], [[3k7m|3k7m]], [[3k7q|3k7q]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6-HLNO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29320 Arthrobacter nicotinovorans])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">6-HLNO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29320 Arthrobacter nicotinovorans])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-6-hydroxynicotine_oxidase (S)-6-hydroxynicotine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.5 1.5.3.5] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-6-hydroxynicotine_oxidase (S)-6-hydroxynicotine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.3.5 1.5.3.5] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk0 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk0 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nk0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nk0 RCSB], [http://www.ebi.ac.uk/pdbsum/3nk0 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.,Kachalova GS, Bourenkov GP, Mengesdorf T, Schenk S, Maun HR, Burghammer M, Riekel C, Decker K, Bartunik HD J Mol Biol. 2010 Feb 26;396(3):785-99. Epub 2009 Dec 16. PMID:20006620<ref>PMID:20006620</ref> | Crystal structure analysis of free and substrate-bound 6-hydroxy-L-nicotine oxidase from Arthrobacter nicotinovorans.,Kachalova GS, Bourenkov GP, Mengesdorf T, Schenk S, Maun HR, Burghammer M, Riekel C, Decker K, Bartunik HD J Mol Biol. 2010 Feb 26;396(3):785-99. Epub 2009 Dec 16. PMID:20006620<ref>PMID:20006620</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Arthrobacter nicotinovorans]] | [[Category: Arthrobacter nicotinovorans]] | ||
| - | [[Category: Bartunik, H D | + | [[Category: Bartunik, H D]] |
| - | [[Category: Kachalova, G S | + | [[Category: Kachalova, G S]] |
[[Category: Enanthiomeric substrate-inhibitor]] | [[Category: Enanthiomeric substrate-inhibitor]] | ||
[[Category: Flavoenzyme]] | [[Category: Flavoenzyme]] | ||
[[Category: Nicotine degradation]] | [[Category: Nicotine degradation]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
Revision as of 21:16, 3 January 2015
Complex of 6-hydroxy-L-nicotine oxidase with inhibitor bound at active site and turnover product at exit cavity
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