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3mau
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3mau]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Symbiobacterium_thermophilum Symbiobacterium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MAU FirstGlance]. <br> | <table><tr><td colspan='2'>[[3mau]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Symbiobacterium_thermophilum Symbiobacterium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MAU FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EXT:{5-HYDROXY-6-METHYL-4-[(E)-{[2-(PHOSPHONOOXY)ETHYL]IMINO}METHYL]PYRIDIN-3-YL}METHYL+DIHYDROGEN+PHOSPHATE'>EXT</scene>, <scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EXT:{5-HYDROXY-6-METHYL-4-[(E)-{[2-(PHOSPHONOOXY)ETHYL]IMINO}METHYL]PYRIDIN-3-YL}METHYL+DIHYDROGEN+PHOSPHATE'>EXT</scene>, <scene name='pdbligand=PLR:(5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL+DIHYDROGEN+PHOSPHATE'>PLR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mad|3mad]], [[3maf|3maf]], [[3mc6|3mc6]], [[3mbb|3mbb]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mad|3mad]], [[3maf|3maf]], [[3mc6|3mc6]], [[3mbb|3mbb]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STH1274 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2734 Symbiobacterium thermophilum])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STH1274 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2734 Symbiobacterium thermophilum])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sphinganine-1-phosphate_aldolase Sphinganine-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.27 4.1.2.27] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sphinganine-1-phosphate_aldolase Sphinganine-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.27 4.1.2.27] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mau RCSB], [http://www.ebi.ac.uk/pdbsum/3mau PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mau RCSB], [http://www.ebi.ac.uk/pdbsum/3mau PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism.,Bourquin F, Riezman H, Capitani G, Grutter MG Structure. 2010 Aug 11;18(8):1054-65. PMID:20696404<ref>PMID:20696404</ref> | Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism.,Bourquin F, Riezman H, Capitani G, Grutter MG Structure. 2010 Aug 11;18(8):1054-65. PMID:20696404<ref>PMID:20696404</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
| Line 33: | Line 33: | ||
[[Category: Sphinganine-1-phosphate aldolase]] | [[Category: Sphinganine-1-phosphate aldolase]] | ||
[[Category: Symbiobacterium thermophilum]] | [[Category: Symbiobacterium thermophilum]] | ||
| - | [[Category: Bourquin, F | + | [[Category: Bourquin, F]] |
| - | [[Category: Capitani, G | + | [[Category: Capitani, G]] |
| - | [[Category: Grutter, M G | + | [[Category: Grutter, M G]] |
[[Category: Carboxy-lyase activity]] | [[Category: Carboxy-lyase activity]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Pyridoxyl phosphate]] | [[Category: Pyridoxyl phosphate]] | ||
Revision as of 22:50, 3 January 2015
Crystal structure of StSPL in complex with phosphoethanolamine
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