3nd5

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3nd5]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ND5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ND5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3nd5]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ND5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ND5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nd6|3nd6]], [[3nd7|3nd7]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nd6|3nd6]], [[3nd7|3nd7]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 Enterococcus faecalis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1351 Enterococcus faecalis])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nd5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nd5 RCSB], [http://www.ebi.ac.uk/pdbsum/3nd5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nd5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nd5 RCSB], [http://www.ebi.ac.uk/pdbsum/3nd5 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/COAD_ENTFA COAD_ENTFA]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine.,Yoon HJ, Kang JY, Mikami B, Lee HH, Suh SW Mol Cells. 2011 Nov;32(5):431-5. Epub 2011 Sep 9. PMID:21912874<ref>PMID:21912874</ref>
Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine.,Yoon HJ, Kang JY, Mikami B, Lee HH, Suh SW Mol Cells. 2011 Nov;32(5):431-5. Epub 2011 Sep 9. PMID:21912874<ref>PMID:21912874</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
== References ==
== References ==
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[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
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[[Category: Lee, H H.]]
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[[Category: Lee, H H]]
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[[Category: Suh, S W.]]
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[[Category: Suh, S W]]
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[[Category: Yoon, H J.]]
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[[Category: Yoon, H J]]
[[Category: Coenzyme a biosynthetic pathway]]
[[Category: Coenzyme a biosynthetic pathway]]
[[Category: Phosphopantetheine adenylyltransferase]]
[[Category: Phosphopantetheine adenylyltransferase]]
[[Category: Ppat]]
[[Category: Ppat]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 14:08, 24 December 2014

Crystal structure of phosphopantetheine adenylyltransferase (PPAT) from Enterococcus faecalis

3nd5, resolution 2.30Å

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