3q8t
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q8T FirstGlance]. <br> | <table><tr><td colspan='2'>[[3q8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q8T FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Becn1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Becn1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q8t RCSB], [http://www.ebi.ac.uk/pdbsum/3q8t PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q8t RCSB], [http://www.ebi.ac.uk/pdbsum/3q8t PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BECN1_RAT BECN1_RAT]] Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.,Li X, He L, Che KH, Funderburk SF, Pan L, Pan N, Zhang M, Yue Z, Zhao Y Nat Commun. 2012 Feb 7;3:662. doi: 10.1038/ncomms1648. PMID:22314358<ref>PMID:22314358</ref> | Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG.,Li X, He L, Che KH, Funderburk SF, Pan L, Pan N, Zhang M, Yue Z, Zhao Y Nat Commun. 2012 Feb 7;3:662. doi: 10.1038/ncomms1648. PMID:22314358<ref>PMID:22314358</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Li, X | + | [[Category: Li, X]] |
| - | [[Category: Zhao, Y | + | [[Category: Zhao, Y]] |
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Atg14l uvrag]] | [[Category: Atg14l uvrag]] | ||
[[Category: Autophagy]] | [[Category: Autophagy]] | ||
Revision as of 14:27, 25 December 2014
Crystal structure of the coiled coil domain of Beclin 1, an essential autophagy protein
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