3q0v
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q0v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q0V FirstGlance]. <br> | <table><tr><td colspan='2'>[[3q0v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q0V FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LL4:4-METHYL-1-{4-[3-(THIOPHEN-2-YL)-1,2,4-OXADIAZOL-5-YL]PIPERIDIN-1-YL}PENTAN-1-ONE'>LL4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LL4:4-METHYL-1-{4-[3-(THIOPHEN-2-YL)-1,2,4-OXADIAZOL-5-YL]PIPERIDIN-1-YL}PENTAN-1-ONE'>LL4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o8g|3o8g]], [[3o8l|3o8l]], [[3g1m|3g1m]], [[3g1l|3g1l]], [[3g1o|3g1o]], [[1u9n|1u9n]], [[3q0u|3q0u]], [[3q0w|3q0w]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3o8g|3o8g]], [[3o8l|3o8l]], [[3g1m|3g1m]], [[3g1l|3g1l]], [[3g1o|3g1o]], [[1u9n|1u9n]], [[3q0u|3q0u]], [[3q0w|3q0w]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ethR, etaR, MT3970, Rv3855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ethR, etaR, MT3970, Rv3855 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q0v RCSB], [http://www.ebi.ac.uk/pdbsum/3q0v PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q0v RCSB], [http://www.ebi.ac.uk/pdbsum/3q0v PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Baulard, A | + | [[Category: Baulard, A]] |
| - | [[Category: Brodin, P | + | [[Category: Brodin, P]] |
| - | [[Category: Carette, X | + | [[Category: Carette, X]] |
| - | [[Category: Christophe, T | + | [[Category: Christophe, T]] |
| - | [[Category: Demirkaya, F | + | [[Category: Demirkaya, F]] |
| - | [[Category: Deprez, B | + | [[Category: Deprez, B]] |
| - | [[Category: Desroses, M | + | [[Category: Desroses, M]] |
| - | [[Category: Dirie, B | + | [[Category: Dirie, B]] |
| - | [[Category: Flipo, M | + | [[Category: Flipo, M]] |
| - | [[Category: Jeon, H K | + | [[Category: Jeon, H K]] |
| - | [[Category: Lens, Z | + | [[Category: Lens, Z]] |
| - | [[Category: Leroux, F | + | [[Category: Leroux, F]] |
| - | [[Category: Locht, C | + | [[Category: Locht, C]] |
| - | [[Category: Piveteau, C | + | [[Category: Piveteau, C]] |
| - | [[Category: Rucktooa, P | + | [[Category: Rucktooa, P]] |
| - | [[Category: Villeret, V | + | [[Category: Villeret, V]] |
| - | [[Category: Willand, N | + | [[Category: Willand, N]] |
[[Category: Tetr family]] | [[Category: Tetr family]] | ||
[[Category: Transcription-transcription inhibitor complex]] | [[Category: Transcription-transcription inhibitor complex]] | ||
[[Category: Transcriptional repressor]] | [[Category: Transcriptional repressor]] | ||
Revision as of 13:59, 25 December 2014
ETHR From mycobacterium tuberculosis in complex with compound bdm31369
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Categories: Mycobacterium tuberculosis | Baulard, A | Brodin, P | Carette, X | Christophe, T | Demirkaya, F | Deprez, B | Desroses, M | Dirie, B | Flipo, M | Jeon, H K | Lens, Z | Leroux, F | Locht, C | Piveteau, C | Rucktooa, P | Villeret, V | Willand, N | Tetr family | Transcription-transcription inhibitor complex | Transcriptional repressor
