3q0j

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3q0j]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q0J FirstGlance]. <br>
<table><tr><td colspan='2'>[[3q0j]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q0J FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pzk|3pzk]], [[3q0g|3q0g]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pzk|3pzk]], [[3q0g|3q0g]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">echA8, MT1100, MTV017.23c, Rv1070c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">echA8, MT1100, MTV017.23c, Rv1070c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-CoA_hydratase Enoyl-CoA hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.17 4.2.1.17] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-CoA_hydratase Enoyl-CoA hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.17 4.2.1.17] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q0j RCSB], [http://www.ebi.ac.uk/pdbsum/3q0j PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q0j RCSB], [http://www.ebi.ac.uk/pdbsum/3q0j PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/ECHA8_MYCTU ECHA8_MYCTU]] Could possibly oxidize fatty acids using specific components (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Enoyl-CoA hydratase]]
[[Category: Enoyl-CoA hydratase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Bruning, J B.]]
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[[Category: Bruning, J B]]
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[[Category: Delgado, E.]]
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[[Category: Delgado, E]]
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[[Category: Ghosh, S.]]
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[[Category: Ghosh, S]]
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[[Category: Sacchettini, J C.]]
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[[Category: Sacchettini, J C]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
[[Category: Crotonase]]
[[Category: Crotonase]]
[[Category: Enoyl coa hydratase]]
[[Category: Enoyl coa hydratase]]
[[Category: Lyase]]
[[Category: Lyase]]
[[Category: Lyase-lyase inhibitor complex]]
[[Category: Lyase-lyase inhibitor complex]]
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[[Category: Structural genomic]]
 
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[[Category: Tb structural genomics consortium]]
 
[[Category: Tbsgc]]
[[Category: Tbsgc]]

Revision as of 08:35, 24 December 2014

Crystal Structure of the Mycobacterium tuberculosis Crotonase in complex with the Inhibitor AcetoacetylCoA

3q0j, resolution 2.40Å

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