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3qzr
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3qzr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QZR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QZR FirstGlance]. <br> | <table><tr><td colspan='2'>[[3qzr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_enterovirus_71 Human enterovirus 71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QZR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QZR FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AG7:4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC+ACID+ETHYL+ESTER'>AG7</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AG7:4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC+ACID+ETHYL+ESTER'>AG7</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3osy|3osy]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3osy|3osy]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">polyprotein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39054 Human enterovirus 71])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">polyprotein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=39054 Human enterovirus 71])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qzr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qzr RCSB], [http://www.ebi.ac.uk/pdbsum/3qzr PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qzr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qzr RCSB], [http://www.ebi.ac.uk/pdbsum/3qzr PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 14: | Line 14: | ||
Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of the Catalytically Important Residues.,Wang J, Fan T, Yao X, Wu Z, Guo L, Lei X, Wang J, Wang M, Jin Q, Cui S J Virol. 2011 Aug 3. PMID:21813612<ref>PMID:21813612</ref> | Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of the Catalytically Important Residues.,Wang J, Fan T, Yao X, Wu Z, Guo L, Lei X, Wang J, Wang M, Jin Q, Cui S J Virol. 2011 Aug 3. PMID:21813612<ref>PMID:21813612</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human enterovirus 71]] | [[Category: Human enterovirus 71]] | ||
| - | [[Category: Cui, S | + | [[Category: Cui, S]] |
| - | [[Category: Fan, T | + | [[Category: Fan, T]] |
| - | [[Category: Guo, L | + | [[Category: Guo, L]] |
| - | [[Category: Jin, Q | + | [[Category: Jin, Q]] |
| - | [[Category: Lei, X | + | [[Category: Lei, X]] |
| - | [[Category: Wang, J | + | [[Category: Wang, J]] |
| - | [[Category: Wang, M | + | [[Category: Wang, M]] |
| - | [[Category: Wu, Z | + | [[Category: Wu, Z]] |
| - | [[Category: Yao, X | + | [[Category: Yao, X]] |
[[Category: Beta-ribbon]] | [[Category: Beta-ribbon]] | ||
[[Category: Chymotrypsin-fold]] | [[Category: Chymotrypsin-fold]] | ||
Revision as of 21:05, 3 January 2015
Human enterovirus 71 3C protease mutant E71A in complex with rupintrivir
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Categories: Human enterovirus 71 | Cui, S | Fan, T | Guo, L | Jin, Q | Lei, X | Wang, J | Wang, M | Wu, Z | Yao, X | Beta-ribbon | Chymotrypsin-fold | Hydrolase-hydrolase inhibitor complex | Hydrolysis | Nucleus
