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3r6b
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3r6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R6B FirstGlance]. <br> | <table><tr><td colspan='2'>[[3r6b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R6B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R6B FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lsl|1lsl]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lsl|1lsl]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THBS1, TSP, TSP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">THBS1, TSP, TSP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r6b RCSB], [http://www.ebi.ac.uk/pdbsum/3r6b PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r6b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r6b RCSB], [http://www.ebi.ac.uk/pdbsum/3r6b PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/TSP1_HUMAN TSP1_HUMAN]] Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties.<ref>PMID:11134179</ref> <ref>PMID:15014436</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.,Klenotic PA, Page RC, Misra S, Silverstein RL Protein Expr Purif. 2011 Jul 29. PMID:21821127<ref>PMID:21821127</ref> | Expression, purification and structural characterization of functionally replete thrombospondin-1 type 1 repeats in a bacterial expression system.,Klenotic PA, Page RC, Misra S, Silverstein RL Protein Expr Purif. 2011 Jul 29. PMID:21821127<ref>PMID:21821127</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Klenotic, P A | + | [[Category: Klenotic, P A]] |
| - | [[Category: Misra, S | + | [[Category: Misra, S]] |
| - | [[Category: Page, R C | + | [[Category: Page, R C]] |
| - | [[Category: Silverstein, R L | + | [[Category: Silverstein, R L]] |
[[Category: Cell adhesion]] | [[Category: Cell adhesion]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Egf-like domain]] | [[Category: Egf-like domain]] | ||
[[Category: Tsp-1 type 1 repeat]] | [[Category: Tsp-1 type 1 repeat]] | ||
Revision as of 21:06, 25 December 2014
Crystal Structure of Thrombospondin-1 TSR Domains 2 and 3
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