3qxr

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qxr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QXR FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qxr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QXR FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qxr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qxr RCSB], [http://www.ebi.ac.uk/pdbsum/3qxr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qxr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qxr RCSB], [http://www.ebi.ac.uk/pdbsum/3qxr PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation.,Wei D, Parkinson GN, Reszka AP, Neidle S Nucleic Acids Res. 2012 Jan 28. PMID:22287624<ref>PMID:22287624</ref>
Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation.,Wei D, Parkinson GN, Reszka AP, Neidle S Nucleic Acids Res. 2012 Jan 28. PMID:22287624<ref>PMID:22287624</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Neidle, S.]]
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[[Category: Neidle, S]]
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[[Category: Parkinson, G N.]]
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[[Category: Parkinson, G N]]
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[[Category: Wei, D.]]
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[[Category: Wei, D]]
[[Category: Ckit-1]]
[[Category: Ckit-1]]
[[Category: Dna]]
[[Category: Dna]]
[[Category: Dna quadruplex]]
[[Category: Dna quadruplex]]
[[Category: Regulation]]
[[Category: Regulation]]

Revision as of 22:39, 3 January 2015

Crystal structure of the brominated CKIT-1 proto-oncogene promoter quadruplex DNA

3qxr, resolution 1.62Å

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