3rpu

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3rpu]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[3rpu]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RPU FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3euh|3euh]], [[3euj|3euj]], [[3euk|3euk]], [[1t98|1t98]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3euh|3euh]], [[3euj|3euj]], [[3euk|3euk]], [[1t98|1t98]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0922, JW0905, kicB, mukF, mukF (kicB) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), b0923, JW0906, kicA, mukE, MukE (kicA, ycbA, ycbA) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0922, JW0905, kicB, mukF, mukF (kicB) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), b0923, JW0906, kicA, mukE, MukE (kicA, ycbA, ycbA) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rpu RCSB], [http://www.ebi.ac.uk/pdbsum/3rpu PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rpu RCSB], [http://www.ebi.ac.uk/pdbsum/3rpu PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/MUKF_ECOLI MUKF_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.<ref>PMID:8602138</ref> [[http://www.uniprot.org/uniprot/MUKE_ECOLI MUKE_ECOLI]] Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.<ref>PMID:8602138</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The role of MukE in assembling a functional MukBEF complex.,Gloyd M, Ghirlando R, Guarne A J Mol Biol. 2011 Sep 30;412(4):578-90. Epub 2011 Aug 10. PMID:21855551<ref>PMID:21855551</ref>
The role of MukE in assembling a functional MukBEF complex.,Gloyd M, Ghirlando R, Guarne A J Mol Biol. 2011 Sep 30;412(4):578-90. Epub 2011 Aug 10. PMID:21855551<ref>PMID:21855551</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Ghirlando, R.]]
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[[Category: Ghirlando, R]]
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[[Category: Gloyd, M.]]
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[[Category: Gloyd, M]]
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[[Category: Guarne, A.]]
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[[Category: Guarne, A]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Chromosome condensation and segregation]]
[[Category: Chromosome condensation and segregation]]

Revision as of 06:40, 25 December 2014

Crystal structure of the MukE-MukF complex

3rpu, resolution 3.60Å

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