3rwv
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3rwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWV FirstGlance]. <br> | <table><tr><td colspan='2'>[[3rwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWV FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2evt|2evt]], [[1swx|1swx]], [[3rzn|3rzn]], [[3s0i|3s0i]], [[3s0k|3s0k]], [[3ric|3ric]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2evt|2evt]], [[1swx|1swx]], [[3rzn|3rzn]], [[3s0i|3s0i]], [[3s0k|3s0k]], [[3ric|3ric]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rwv RCSB], [http://www.ebi.ac.uk/pdbsum/3rwv PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rwv RCSB], [http://www.ebi.ac.uk/pdbsum/3rwv PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.,Samygina VR, Popov AN, Cabo-Bilbao A, Ochoa-Lizarralde B, Goni-de-Cerio F, Zhai X, Molotkovsky JG, Patel DJ, Brown RE, Malinina L Structure. 2011 Nov 9;19(11):1644-54. PMID:22078563<ref>PMID:22078563</ref> | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.,Samygina VR, Popov AN, Cabo-Bilbao A, Ochoa-Lizarralde B, Goni-de-Cerio F, Zhai X, Molotkovsky JG, Patel DJ, Brown RE, Malinina L Structure. 2011 Nov 9;19(11):1644-54. PMID:22078563<ref>PMID:22078563</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Brown, R E | + | [[Category: Brown, R E]] |
| - | [[Category: Cabo-Bilbao, A | + | [[Category: Cabo-Bilbao, A]] |
| - | [[Category: Goni-de-Cerio, F | + | [[Category: Goni-de-Cerio, F]] |
| - | [[Category: Malinina, L | + | [[Category: Malinina, L]] |
| - | [[Category: Ochoa-Lizarralde, B | + | [[Category: Ochoa-Lizarralde, B]] |
| - | [[Category: Patel, D J | + | [[Category: Patel, D J]] |
| - | [[Category: Popov, A N | + | [[Category: Popov, A N]] |
| - | [[Category: Samygina, V | + | [[Category: Samygina, V]] |
[[Category: Gltp-fold]] | [[Category: Gltp-fold]] | ||
[[Category: Lipid transport]] | [[Category: Lipid transport]] | ||
Revision as of 09:32, 25 December 2014
Crystal Structure of apo-form of Human Glycolipid Transfer Protein at 1.5 A resolution
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