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3r2w

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3r2w]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R2W FirstGlance]. <br>
<table><tr><td colspan='2'>[[3r2w]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3R2W FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UGP2, UGP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UGP2, UGP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UTP--glucose-1-phosphate_uridylyltransferase UTP--glucose-1-phosphate uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.9 2.7.7.9] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UTP--glucose-1-phosphate_uridylyltransferase UTP--glucose-1-phosphate uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.9 2.7.7.9] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r2w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r2w RCSB], [http://www.ebi.ac.uk/pdbsum/3r2w PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3r2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r2w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3r2w RCSB], [http://www.ebi.ac.uk/pdbsum/3r2w PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/UGPA_HUMAN UGPA_HUMAN]] Plays a central role as a glucosyl donor in cellular metabolic pathways.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influence enzymatic activity.,Yu Q, Zheng X Biochem J. 2011 Dec 1. PMID:22132858<ref>PMID:22132858</ref>
The crystal structure of human UDP-glucose pyrophosphorylase reveals a latch effect that influence enzymatic activity.,Yu Q, Zheng X Biochem J. 2011 Dec 1. PMID:22132858<ref>PMID:22132858</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: UTP--glucose-1-phosphate uridylyltransferase]]
[[Category: UTP--glucose-1-phosphate uridylyltransferase]]
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[[Category: Yu, Q.]]
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[[Category: Yu, Q]]
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[[Category: Zheng, X.]]
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[[Category: Zheng, X]]
[[Category: Homo sapien]]
[[Category: Homo sapien]]
[[Category: Nucleotidyltransferase]]
[[Category: Nucleotidyltransferase]]
[[Category: Rossmann fold beta barrel]]
[[Category: Rossmann fold beta barrel]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 07:02, 24 December 2014

Crystal Strucutre of UDP-glucose Pyrophosphorylase of Homo Sapiens

3r2w, resolution 3.60Å

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