3s0k
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3s0k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S0K FirstGlance]. <br> | <table><tr><td colspan='2'>[[3s0k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S0K FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03F:(9Z)-N-[(2S,3R,4E)-1-(BETA-D-GLUCOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]OCTADEC-9-ENAMIDE'>03F</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03F:(9Z)-N-[(2S,3R,4E)-1-(BETA-D-GLUCOPYRANOSYLOXY)-3-HYDROXYOCTADEC-4-EN-2-YL]OCTADEC-9-ENAMIDE'>03F</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rwv|3rwv]], [[2euk|2euk]], [[1swx|1swx]], [[3rzn|3rzn]], [[3ric|3ric]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3rwv|3rwv]], [[2euk|2euk]], [[1swx|1swx]], [[3rzn|3rzn]], [[3ric|3ric]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s0k RCSB], [http://www.ebi.ac.uk/pdbsum/3s0k PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s0k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s0k RCSB], [http://www.ebi.ac.uk/pdbsum/3s0k PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.,Samygina VR, Popov AN, Cabo-Bilbao A, Ochoa-Lizarralde B, Goni-de-Cerio F, Zhai X, Molotkovsky JG, Patel DJ, Brown RE, Malinina L Structure. 2011 Nov 9;19(11):1644-54. PMID:22078563<ref>PMID:22078563</ref> | Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.,Samygina VR, Popov AN, Cabo-Bilbao A, Ochoa-Lizarralde B, Goni-de-Cerio F, Zhai X, Molotkovsky JG, Patel DJ, Brown RE, Malinina L Structure. 2011 Nov 9;19(11):1644-54. PMID:22078563<ref>PMID:22078563</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Brown, R E | + | [[Category: Brown, R E]] |
| - | [[Category: Cabo-Bilbao, A | + | [[Category: Cabo-Bilbao, A]] |
| - | [[Category: Goni-de-Cerio, F | + | [[Category: Goni-de-Cerio, F]] |
| - | [[Category: Malinina, L | + | [[Category: Malinina, L]] |
| - | [[Category: Ochoa-Lizarralde, B | + | [[Category: Ochoa-Lizarralde, B]] |
| - | [[Category: Patel, D J | + | [[Category: Patel, D J]] |
| - | [[Category: Popov, A N | + | [[Category: Popov, A N]] |
| - | [[Category: Samygina, V | + | [[Category: Samygina, V]] |
[[Category: Gltp-fold]] | [[Category: Gltp-fold]] | ||
[[Category: Lipid transport]] | [[Category: Lipid transport]] | ||
Revision as of 19:34, 24 December 2014
Crystal Structure of Human Glycolipid Transfer Protein complexed with glucosylceramide containing oleoyl acyl chain (18:1)
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