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3qsf
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3qsf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QSF FirstGlance]. <br> | <table><tr><td colspan='2'>[[3qsf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QSF FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NUF:[2,2-{(4,5-DIFLUOROBENZENE-1,2-DIYL)BIS[(NITRILO-KAPPAN)METHYLYLIDENE]}BIS{5-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOLATO-KAPPAO}(2-)]NICKEL+(II)'>NUF</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NUF:[2,2-{(4,5-DIFLUOROBENZENE-1,2-DIYL)BIS[(NITRILO-KAPPAN)METHYLYLIDENE]}BIS{5-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOLATO-KAPPAO}(2-)]NICKEL+(II)'>NUF</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qsc|3qsc]], [[3ce5|3ce5]], [[3cco|3cco]], [[3cdm|3cdm]], [[1kf1|1kf1]], [[1k8p|1k8p]], [[2hri|2hri]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qsc|3qsc]], [[3ce5|3ce5]], [[3cco|3cco]], [[3cdm|3cdm]], [[1kf1|1kf1]], [[1k8p|1k8p]], [[2hri|2hri]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qsf RCSB], [http://www.ebi.ac.uk/pdbsum/3qsf PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qsf RCSB], [http://www.ebi.ac.uk/pdbsum/3qsf PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.,Campbell NH, Karim N, Parkinson GN, Gunaratnam M, Petrucci V, Todd AK, Vilar R, Neidle S J Med Chem. 2011 Nov 24. PMID:22112241<ref>PMID:22112241</ref> | Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.,Campbell NH, Karim N, Parkinson GN, Gunaratnam M, Petrucci V, Todd AK, Vilar R, Neidle S J Med Chem. 2011 Nov 24. PMID:22112241<ref>PMID:22112241</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Campbell, N H | + | [[Category: Campbell, N H]] |
| - | [[Category: Karim, N H.Abd | + | [[Category: Karim, N H.Abd]] |
| - | [[Category: Neidle, S | + | [[Category: Neidle, S]] |
| - | [[Category: Parkinson, G N | + | [[Category: Parkinson, G N]] |
| - | [[Category: Vilar, R | + | [[Category: Vilar, R]] |
[[Category: Dna]] | [[Category: Dna]] | ||
[[Category: Drug]] | [[Category: Drug]] | ||
Revision as of 21:31, 3 January 2015
The first crystal structure of a human telomeric G-quadruplex DNA bound to a metal-containing ligand (a nickel complex)
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Categories: Campbell, N H | Karim, N H.Abd | Neidle, S | Parkinson, G N | Vilar, R | Dna | Drug | Metal complex | Nickel | Parallel | Telomere
