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3sbz

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3sbz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SBZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3sbz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SBZ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sby|3sby]], [[3sc0|3sc0]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sby|3sby]], [[3sc0|3sc0]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMACHC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MMACHC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sbz RCSB], [http://www.ebi.ac.uk/pdbsum/3sbz PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3sbz RCSB], [http://www.ebi.ac.uk/pdbsum/3sbz PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN]] Methylmalonic acidemia with homocystinuria, type cblC. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN]] Methylmalonic acidemia with homocystinuria, type cblC. The disease is caused by mutations affecting the gene represented in this entry.
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The structural basis of multifunctionality in a B12 processing enzyme.,Koutmos M, Gherasim C, Smith JL, Banerjee R J Biol Chem. 2011 Jun 22. PMID:21697092<ref>PMID:21697092</ref>
The structural basis of multifunctionality in a B12 processing enzyme.,Koutmos M, Gherasim C, Smith JL, Banerjee R J Biol Chem. 2011 Jun 22. PMID:21697092<ref>PMID:21697092</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Banerjee, R.]]
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[[Category: Banerjee, R]]
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[[Category: Gherasim, C.]]
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[[Category: Gherasim, C]]
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[[Category: Koutmos, M.]]
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[[Category: Koutmos, M]]
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[[Category: Smith, J L.]]
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[[Category: Smith, J L]]
[[Category: Cblc]]
[[Category: Cblc]]
[[Category: Cobalamin]]
[[Category: Cobalamin]]

Revision as of 09:43, 4 January 2015

Crystal Structure of Apo-MMACHC (1-244), a human B12 processing enzyme

3sbz, resolution 2.00Å

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