3srk
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3srk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SRK FirstGlance]. <br> | <table><tr><td colspan='2'>[[3srk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Leishmania_mexicana Leishmania mexicana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SRK FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=PTK:PYRENE-1,3,6,8-TETRASULFONIC+ACID'>PTK</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LSA:1,2-BENZISOTHIAZOL-3(2H)-ONE+1,1-DIOXIDE'>LSA</scene>, <scene name='pdbligand=PTK:PYRENE-1,3,6,8-TETRASULFONIC+ACID'>PTK</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pkl|1pkl]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pkl|1pkl]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5665 Leishmania mexicana])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PYK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5665 Leishmania mexicana])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr> | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3srk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3srk RCSB], [http://www.ebi.ac.uk/pdbsum/3srk PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3srk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3srk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3srk RCSB], [http://www.ebi.ac.uk/pdbsum/3srk PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
==See Also== | ==See Also== | ||
| Line 16: | Line 16: | ||
[[Category: Leishmania mexicana]] | [[Category: Leishmania mexicana]] | ||
[[Category: Pyruvate kinase]] | [[Category: Pyruvate kinase]] | ||
| - | [[Category: Auld, D S | + | [[Category: Auld, D S]] |
| - | [[Category: Blackburn, E A | + | [[Category: Blackburn, E A]] |
| - | [[Category: Boxer, M | + | [[Category: Boxer, M]] |
| - | [[Category: Fothergill-Gilmore, L A | + | [[Category: Fothergill-Gilmore, L A]] |
| - | [[Category: McNae, I W | + | [[Category: McNae, I W]] |
| - | [[Category: Michels, P A.M | + | [[Category: Michels, P A.M]] |
| - | [[Category: Morgan, H P | + | [[Category: Morgan, H P]] |
| - | [[Category: Shen, M | + | [[Category: Shen, M]] |
| - | [[Category: Walkinshaw, M D | + | [[Category: Walkinshaw, M D]] |
| - | [[Category: Walsh, M | + | [[Category: Walsh, M]] |
| - | [[Category: Wear, M A | + | [[Category: Wear, M A]] |
[[Category: Phosphenolpyruvate]] | [[Category: Phosphenolpyruvate]] | ||
[[Category: Phospho transfer]] | [[Category: Phospho transfer]] | ||
Revision as of 10:27, 4 January 2015
A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
| |||||||||||
Categories: Leishmania mexicana | Pyruvate kinase | Auld, D S | Blackburn, E A | Boxer, M | Fothergill-Gilmore, L A | McNae, I W | Michels, P A.M | Morgan, H P | Shen, M | Walkinshaw, M D | Walsh, M | Wear, M A | Phosphenolpyruvate | Phospho transfer | Sugar kinase | Tim barrel | Transferase-inhibitor complex
