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3v71

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V71 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3v71]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V71 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V71 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v6y|3v6y]], [[3v74|3v74]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3v6y|3v6y]], [[3v74|3v74]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">puf-7, B0273.2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">puf-7, B0273.2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [http://www.ebi.ac.uk/pdbsum/3v71 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v71 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v71 RCSB], [http://www.ebi.ac.uk/pdbsum/3v71 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/O44169_CAEEL O44169_CAEEL]] RNA-binding protein that binds to the consensus sequence 5'-CUCUGUAUCUUGU-3' in mRNA 3'-UTRs and modulates mRNA expression and stability. Functions redundantly with puf-5 and puf-6 in oocyte formation and organization, early embryonic cell divisions, and repression of expression of glp-1 and other maternal mRNAs in late oogenesis.<ref>PMID:17234175</ref> <ref>PMID:22542599</ref> <ref>PMID:22205700</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
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[[Category: Hall, T M.T.]]
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[[Category: Hall, T M.T]]
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[[Category: Holley, C H.]]
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[[Category: Holley, C H]]
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[[Category: Keles, S.]]
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[[Category: Keles, S]]
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[[Category: Kershner, A.]]
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[[Category: Kershner, A]]
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[[Category: Kimble, J.]]
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[[Category: Kimble, J]]
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[[Category: Qiu, C.]]
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[[Category: Qiu, C]]
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[[Category: Wang, Y.]]
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[[Category: Wang, Y]]
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[[Category: Wickens, M.]]
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[[Category: Wickens, M]]
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[[Category: Wilinski, D.]]
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[[Category: Wilinski, D]]
[[Category: Puf repeat]]
[[Category: Puf repeat]]
[[Category: Rna binding protein-rna complex]]
[[Category: Rna binding protein-rna complex]]

Revision as of 08:29, 24 December 2014

Crystal structure of PUF-6 in complex with 5BE13 RNA

3v71, resolution 2.90Å

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