3uxu
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3uxu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_1 Sulfolobus virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UXU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UXU FirstGlance]. <br> | <table><tr><td colspan='2'>[[3uxu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_virus_1 Sulfolobus virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UXU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UXU FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">d335 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=244589 Sulfolobus virus 1])</td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">d335 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=244589 Sulfolobus virus 1])</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uxu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uxu RCSB], [http://www.ebi.ac.uk/pdbsum/3uxu PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uxu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uxu RCSB], [http://www.ebi.ac.uk/pdbsum/3uxu PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/INTG_SSV1 INTG_SSV1]] This protein may encode a site-specific integrase, which is necessary for integration of the phage by site-specific recombination into a tRNA gene of the host chromosome. Essential for virus infection. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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The Structure of an Archaeal Viral Integrase Reveals an Evolutionarily Conserved Catalytic Core yet Supports a Mechanism of DNA Cleavage in trans.,Eilers BJ, Young MJ, Lawrence CM J Virol. 2012 Aug;86(15):8309-13. Epub 2012 May 16. PMID:22593158<ref>PMID:22593158</ref> | The Structure of an Archaeal Viral Integrase Reveals an Evolutionarily Conserved Catalytic Core yet Supports a Mechanism of DNA Cleavage in trans.,Eilers BJ, Young MJ, Lawrence CM J Virol. 2012 Aug;86(15):8309-13. Epub 2012 May 16. PMID:22593158<ref>PMID:22593158</ref> | ||
| - | From | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Sulfolobus virus 1]] | [[Category: Sulfolobus virus 1]] | ||
| - | [[Category: Eilers, B J | + | [[Category: Eilers, B J]] |
| - | [[Category: Lawrence, C M | + | [[Category: Lawrence, C M]] |
| - | [[Category: Young, M J | + | [[Category: Young, M J]] |
[[Category: Archaea]] | [[Category: Archaea]] | ||
[[Category: Archaeal virus]] | [[Category: Archaeal virus]] | ||
Revision as of 12:43, 25 December 2014
The structure of the catalytic domain of the Sulfolobus Spindle-shaped viral integrase reveals an evolutionarily conserved catalytic core and supports a mechanism of DNA cleavage in trans
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