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3tg7
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3tg7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TG7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TG7 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3tg7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_5 Human adenovirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TG7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TG7 FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tg7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tg7 RCSB], [http://www.ebi.ac.uk/pdbsum/3tg7 PDBsum]</span></td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tg7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tg7 RCSB], [http://www.ebi.ac.uk/pdbsum/3tg7 PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HEX_ADE05 HEX_ADE05]] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein (By similarity). Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human adenovirus 5]] | [[Category: Human adenovirus 5]] | ||
| - | [[Category: Baker, A H | + | [[Category: Baker, A H]] |
| - | [[Category: Isaacs, N W | + | [[Category: Isaacs, N W]] |
| - | [[Category: McVey, J H | + | [[Category: McVey, J H]] |
| - | [[Category: Nicklin, S A | + | [[Category: Nicklin, S A]] |
| - | [[Category: Roszak, A W | + | [[Category: Roszak, A W]] |
| - | [[Category: Zhu, Y | + | [[Category: Zhu, Y]] |
[[Category: Adenovirus structural protein]] | [[Category: Adenovirus structural protein]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
[[Category: With new finding featuring possible binding to human coagulation factor x]] | [[Category: With new finding featuring possible binding to human coagulation factor x]] | ||
Revision as of 21:36, 25 December 2014
Crystal structure of Adenovirus serotype 5 hexon at 1.6A resolution
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