3u7n

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3u7n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7N FirstGlance]. <br>
<table><tr><td colspan='2'>[[3u7n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7N FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UHF:N-((2R,4S)-2-BUTYL-5-METHYL-4-(3-(5-METHYLPYRIDIN-2-YL)UREIDO)-3-OXOHEXYL)-N-HYDROXYFORMAMIDE'>UHF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UHF:N-((2R,4S)-2-BUTYL-5-METHYL-4-(3-(5-METHYLPYRIDIN-2-YL)UREIDO)-3-OXOHEXYL)-N-HYDROXYFORMAMIDE'>UHF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u7k|3u7k]], [[3u7l|3u7l]], [[3u7m|3u7m]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3u7k|3u7k]], [[3u7l|3u7l]], [[3u7m|3u7m]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sacol1100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sacol1100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7n RCSB], [http://www.ebi.ac.uk/pdbsum/3u7n PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7n RCSB], [http://www.ebi.ac.uk/pdbsum/3u7n PDBsum]</span></td></tr>
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<table>
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</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Peptide deformylase]]
[[Category: Peptide deformylase]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Kim, K K.]]
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[[Category: Kim, K K]]
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[[Category: Lee, B J.]]
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[[Category: Lee, B J]]
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[[Category: Lee, H H.]]
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[[Category: Lee, H H]]
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[[Category: Lee, S J.]]
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[[Category: Lee, S J]]
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[[Category: Lee, S K.]]
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[[Category: Lee, S K]]
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[[Category: Suh, S W.]]
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[[Category: Suh, S W]]
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[[Category: Yoon, H J.]]
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[[Category: Yoon, H J]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Pdf]]
[[Category: Pdf]]
[[Category: Pdf-inhibitor]]
[[Category: Pdf-inhibitor]]
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[[Category: Peptide deformylase]]
 

Revision as of 10:06, 4 January 2015

Crystal structures of the Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors

3u7n, resolution 2.30Å

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