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3vgj

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vgj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VGJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VGJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vgj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VGJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VGJ FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=YAP:5-O-[(R)-{[(2S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANOYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE'>YAP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=YAP:5-O-[(R)-{[(2S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANOYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE'>YAP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q11|1q11]], [[1n3l|1n3l]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1q11|1q11]], [[1n3l|1n3l]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAL8P1.125 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAL8P1.125 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vgj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vgj RCSB], [http://www.ebi.ac.uk/pdbsum/3vgj PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vgj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vgj RCSB], [http://www.ebi.ac.uk/pdbsum/3vgj PDBsum]</span></td></tr>
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<table>
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</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses.,Bhatt TK, Khan S, Dwivedi VP, Banday MM, Sharma A, Chandele A, Camacho N, de Pouplana LR, Wu Y, Craig AG, Mikkonen AT, Maier AG, Yogavel M, Sharma A Nat Commun. 2011 Nov 8;2:530. doi: 10.1038/ncomms1522. PMID:22068597<ref>PMID:22068597</ref>
Malaria parasite tyrosyl-tRNA synthetase secretion triggers pro-inflammatory responses.,Bhatt TK, Khan S, Dwivedi VP, Banday MM, Sharma A, Chandele A, Camacho N, de Pouplana LR, Wu Y, Craig AG, Mikkonen AT, Maier AG, Yogavel M, Sharma A Nat Commun. 2011 Nov 8;2:530. doi: 10.1038/ncomms1522. PMID:22068597<ref>PMID:22068597</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
== References ==
== References ==
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[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Tyrosine--tRNA ligase]]
[[Category: Tyrosine--tRNA ligase]]
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[[Category: Banday, M M.]]
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[[Category: Banday, M M]]
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[[Category: Bhatt, T K.]]
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[[Category: Bhatt, T K]]
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[[Category: Khan, S.]]
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[[Category: Khan, S]]
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[[Category: Sharma, A.]]
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[[Category: Sharma, A]]
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[[Category: Yogavel, M.]]
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[[Category: Yogavel, M]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Synthetase]]
[[Category: Synthetase]]
[[Category: Tyrr]]
[[Category: Tyrr]]

Revision as of 09:19, 4 January 2015

Crystal of Plasmodium falciparum tyrosyl-tRNA synthetase (PfTyrRS)in complex with adenylate analog

3vgj, resolution 2.21Å

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