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4en0

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4en0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ugn 3ugn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EN0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4en0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ugn 3ugn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EN0 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HVEML, LIGHT, TNFSF14, UNQ391/PRO726 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HVEML, LIGHT, TNFSF14, UNQ391/PRO726 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4en0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4en0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4en0 RCSB], [http://www.ebi.ac.uk/pdbsum/4en0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4en0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4en0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4en0 RCSB], [http://www.ebi.ac.uk/pdbsum/4en0 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN]] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Almo, S C.]]
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[[Category: Almo, S C]]
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[[Category: Bonanno, J B.]]
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[[Category: Bonanno, J B]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
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[[Category: IFN, Atoms-to-Animals:.The Immune Function Network]]
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[[Category: Liu, W.]]
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[[Category: Liu, W]]
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[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Nathenson, S G.]]
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[[Category: Nathenson, S G]]
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[[Category: Patskovsky, Y.]]
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[[Category: Patskovsky, Y]]
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[[Category: Ramagopal, U A.]]
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[[Category: Ramagopal, U A]]
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[[Category: Zhan, C.]]
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[[Category: Zhan, C]]
[[Category: Atoms-to-animals: the immune function network]]
[[Category: Atoms-to-animals: the immune function network]]
[[Category: Bind tnf receptor hvem and ltbr]]
[[Category: Bind tnf receptor hvem and ltbr]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: N-glycosylation]]
[[Category: N-glycosylation]]
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[[Category: New york structural genomics research consortium]]
 
[[Category: Nysgrc]]
[[Category: Nysgrc]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
[[Category: Secreted protein]]
[[Category: Secreted protein]]
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[[Category: Structural genomic]]
 
[[Category: Tnf superfamily]]
[[Category: Tnf superfamily]]

Revision as of 07:28, 25 December 2014

Crystal structure of light

4en0, resolution 2.59Å

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