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4a9o
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4a9o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A9O FirstGlance]. <br> | <table><tr><td colspan='2'>[[4a9o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A9O FirstGlance]. <br> | ||
| - | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A9O:5-ETHYL-3-METHYL-4-PHENYL-1,2-OXAZOLE'>A9O</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A9O:5-ETHYL-3-METHYL-4-PHENYL-1,2-OXAZOLE'>A9O</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yek|2yek]], [[4a9e|4a9e]], [[4a9h|4a9h]], [[4a9m|4a9m]], [[4a9f|4a9f]], [[2ydw|2ydw]], [[4a9j|4a9j]], [[1x0j|1x0j]], [[4a9i|4a9i]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yek|2yek]], [[4a9e|4a9e]], [[4a9h|4a9h]], [[4a9m|4a9m]], [[4a9f|4a9f]], [[2ydw|2ydw]], [[4a9j|4a9j]], [[1x0j|1x0j]], [[4a9i|4a9i]]</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a9o RCSB], [http://www.ebi.ac.uk/pdbsum/4a9o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a9o RCSB], [http://www.ebi.ac.uk/pdbsum/4a9o PDBsum]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN]] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Bamborough, P | + | [[Category: Bamborough, P]] |
| - | [[Category: Chung, C W | + | [[Category: Chung, C W]] |
[[Category: Signaling protein-inhibitor complex]] | [[Category: Signaling protein-inhibitor complex]] | ||
Revision as of 18:17, 25 December 2014
N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 5 ethyl-3-methyl-4-phenyl-1, 2-oxazole
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