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4a0p

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a0p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A0P FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a0p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4A0P FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a0p RCSB], [http://www.ebi.ac.uk/pdbsum/4a0p PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4a0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4a0p RCSB], [http://www.ebi.ac.uk/pdbsum/4a0p PDBsum]</span></td></tr>
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<table>
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</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/LRP6_HUMAN LRP6_HUMAN]] Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis. The disease is caused by mutations affecting the gene represented in this entry.
[[http://www.uniprot.org/uniprot/LRP6_HUMAN LRP6_HUMAN]] Coronary artery disease - hyperlipidemia - hypertension - diabetes - osteoporosis. The disease is caused by mutations affecting the gene represented in this entry.
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aricescu, A R.]]
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[[Category: Aricescu, A R]]
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[[Category: Chen, S.]]
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[[Category: Chen, S]]
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[[Category: Jones, E Y.]]
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[[Category: Jones, E Y]]
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[[Category: Malinauskas, T.]]
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[[Category: Malinauskas, T]]
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[[Category: Siebold, C.]]
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[[Category: Siebold, C]]
[[Category: Dkk1]]
[[Category: Dkk1]]
[[Category: Lrp6]]
[[Category: Lrp6]]

Revision as of 09:41, 4 January 2015

Crystal structure of LRP6P3E3P4E4

4a0p, resolution 1.90Å

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