3wg8

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wg8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WG8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wg8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WG8 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AS:(2Z,4E)-5-[(1S)-3-(HEXYLSULFANYL)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>6AS</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AS:(2Z,4E)-5-[(1S)-3-(HEXYLSULFANYL)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>6AS</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wg8 RCSB], [http://www.ebi.ac.uk/pdbsum/3wg8 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wg8 RCSB], [http://www.ebi.ac.uk/pdbsum/3wg8 PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PYR1_ARATH PYR1_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19624469</ref> <ref>PMID:19407142</ref> <ref>PMID:19769575</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Akiyama, T.]]
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[[Category: Akiyama, T]]
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[[Category: Cutler, S R.]]
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[[Category: Cutler, S R]]
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[[Category: Endo, A.]]
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[[Category: Endo, A]]
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[[Category: Hirai, N.]]
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[[Category: Hirai, N]]
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[[Category: Muto, T.]]
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[[Category: Muto, T]]
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[[Category: Nambara, E.]]
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[[Category: Nambara, E]]
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[[Category: Ohnishi, T.]]
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[[Category: Ohnishi, T]]
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[[Category: Okamoto, M.]]
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[[Category: Okamoto, M]]
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[[Category: Sue, M.]]
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[[Category: Sue, M]]
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[[Category: Takeuchi, J.]]
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[[Category: Takeuchi, J]]
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[[Category: Todoroki, Y.]]
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[[Category: Todoroki, Y]]
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[[Category: Yajima, S.]]
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[[Category: Yajima, S]]
[[Category: Abscisic acid]]
[[Category: Abscisic acid]]
[[Category: Hormone receptor]]
[[Category: Hormone receptor]]

Revision as of 17:05, 24 December 2014

Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6

3wg8, resolution 2.30Å

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OCA

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