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Lactoferrin
From Proteopedia
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| - | {{STRUCTURE_1blf| PDB=1blf | SIZE=400| SCENE= |right| CAPTION= | + | {{STRUCTURE_1blf| PDB=1blf | SIZE=400| SCENE= |right| CAPTION=Glycosylated bovine lactoferrin complex with carbonate and Fe+3 ion (orange), [[1blf]] }} |
'''Lactoferrin''' (LTF) is found in secretory fluids. It is a component of the immune system and has antimicrobial activity. LTF interacts with DNA, RNA, polysaccharides and heparin. LTF is inhibited by nonsteroidal anti-inflammatory drugs (NSAID) like aspirin. For detailed discussion of human lactoferrin see [[Human lactoferrin]]. | '''Lactoferrin''' (LTF) is found in secretory fluids. It is a component of the immune system and has antimicrobial activity. LTF interacts with DNA, RNA, polysaccharides and heparin. LTF is inhibited by nonsteroidal anti-inflammatory drugs (NSAID) like aspirin. For detailed discussion of human lactoferrin see [[Human lactoferrin]]. | ||
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== 3D Structures of lactoferrin == | == 3D Structures of lactoferrin == | ||
Revision as of 07:22, 19 August 2014
Lactoferrin (LTF) is found in secretory fluids. It is a component of the immune system and has antimicrobial activity. LTF interacts with DNA, RNA, polysaccharides and heparin. LTF is inhibited by nonsteroidal anti-inflammatory drugs (NSAID) like aspirin. For detailed discussion of human lactoferrin see Human lactoferrin.
Contents |
3D Structures of lactoferrin
Updated on 19-August-2014
Apo lactoferrin
1i6b, 1b7u – hoLTF – horse
1dtz – cLTF - camel
1cb6, 1lfg, 1lfh – hLTF - human
1u62, 1xv4, 1xv7, 1z6v, 1z6w - hLTF peptide – NMR
1lfc – bLTF residues 17-41 – bovine – NMR
1y58, 1y5c - bLTF residues 4-14 – NMR
4oqo – bLTF C lobe
Lactoferrin
1blf – bLTF + 2Fe
1sdx - bLTF C lobe + 3Zn
1nkx, 3u8q - bLTF C lobe + 2Zn + Fe
1b1x, 1f9b – hoLTF + 2Fe
1qjm – hoLTF + 2Sm
1ce2, 1biy – buLTF + 2Fe - buffalo
1i6q – cLTF + 2Fe
2bjj, 1sqy, 1n76– hLTF + 2Fe
1b0l - hLTF (mutant) + 2Fe
1fck – hLTF + 2Ce
1lfi - hLTF + 2Cu
1lct - hLTF N lobe + 2Fe
1h43, 1h44, 1h45, 1l5t, 1eh3, 1vfd, 1vfe, 1hse, 1dsn - hLTF N lobe (mutant) + 2Fe
1jw1 – LTF + 2Fe – goat
Lactoferrin binary complex
3sdf – bLTF C lobe + lipoteichoic acid + 2Zn + Fe
4n6p - bLTF C lobe + meclofenamic acid + 2Zn + Fe
4ned - bLTF C lobe + fenoprofen + 2Zn + Fe
3rgy - bLTF C lobe + lipopolysaccharide + Zn + Fe
3kj7, 3k0v, 2q8j, 2o51, 2nwj, 2dxy, 2dwj, 2dsf, 2ds9, 2hca, 2dqv, 2dp8, 2g93, 2ays, 2alu, 2dwi, 2dyx, 2o1l, 2p1s - bLTF C lobe + polysaccharide + 2Zn + Fe
2o1l - bLTF C lobe + polysaccharide + Zn + Fe
2fa7, 2b65 - bLTF C lobe + polysaccharide + 3Zn + Fe
2dvc, 2dwa, 2dwh, 2e0s, 2e1s, 2h4i, 2px1 - bLTF C lobe + saccharide + 2Zn + Fe
2dxr - bLTF C lobe + sorbitol+ 2Zn + Fe
3iaz, 3ib0, 3ib1 - bLTF C lobe (mutant) + NSAID + 2Zn + Fe
3e9x, 2qje, 2zmb, 3crb, 2nuv, 4fim, 4fjp, 4for, 4g2z, 4g77, 4g8h, 4grk, 3taj - bLTF C lobe + NSAID + 2Zn + Fe
3o97, 3mjn, 3cfl, 2ocu, 3tod, 3tus – bLTF C lobe + inhibitor + 2Zn + Fe
3ib2 - bLTF C lobe (mutant) + inhibitor + 2Zn + Fe
2doj - bLTF C lobe + adenosine + 2Zn + Fe
3ugw - bLTF C lobe + deoxycytidine + 2Zn + Fe
3ci8 - bLTF C lobe + niacin + 2Zn + Fe
2r9j - bLTF C lobe + nicotinamide + 2Zn + Fe
2r71 - bLTF C lobe + inositol + 2Zn + Fe
3uk4 - bLTF C lobe + pentatriol + 2Zn + Fe
3usd - bLTF C lobe + pyridine derivative + 2Zn + Fe
3ttr - bLTF C lobe + anasthetic + 2Zn + Fe
3vdf - bLTF C lobe + diaminopimelic acid + 2Zn + Fe
4dxu - bLTF C lobe + caproic acid + 2Zn + Fe
3v5a - bLTF C lobe + γ-amino butyric acid + 2Zn + Fe
3u72, 4dig - bLTF C lobe + polypeptide + 2Zn + Fe
3ptl – bLTF peptide + proteinase K
1bjr - buLTF peptide + proteinase K
1b7z - hoLTF + 2Fe + oxalate
3cr9 – hoLTF + inhibitor + 2Fe
2j4u – cLTF N terminal + OMPC
1bka - hLTF + 2Fe + oxalate
1lcf - hLTF + 2Cu + oxalate
2pms – hLTF N lobe + PSPA transferring-binding domain + 2Zn + 2Fe
