1brz

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|PDB= 1brz |SIZE=350|CAPTION= <scene name='initialview01'>1brz</scene>
|PDB= 1brz |SIZE=350|CAPTION= <scene name='initialview01'>1brz</scene>
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|LIGAND= <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1brz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brz OCA], [http://www.ebi.ac.uk/pdbsum/1brz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1brz RCSB]</span>
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[[Category: sweet protein]]
[[Category: sweet protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:14:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 19:07:02 2008''

Revision as of 16:07, 30 March 2008


PDB ID 1brz

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Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



SOLUTION STRUCTURE OF THE SWEET PROTEIN BRAZZEIN, NMR, 43 STRUCTURES


Overview

The fruit of Pentadiplandra brazzeana Baillon contains a small, sweet-tasting protein named brazzein. The structure of brazzein in solution was determined by proton nuclear magnetic resonance spectroscopy at pH 5.2 and 22 degrees C. The brazzein fold, which contains one alpha-helix and three strands of antiparallel beta-sheet, does not resemble that of either of the other two sweet-tasting proteins with known structures, monellin and thaumatin. Instead, the structure of brazzein resembles those of plant gamma-thionins and defensins and arthropod toxins. Sequence comparisons predict that members of a newly-identified family of serine proteinase inhibitors share the brazzein fold.

About this Structure

1BRZ is a Single protein structure of sequence from Pentadiplandra brazzeana. Full crystallographic information is available from OCA.

Reference

Solution structure of the thermostable sweet-tasting protein brazzein., Caldwell JE, Abildgaard F, Dzakula Z, Ming D, Hellekant G, Markley JL, Nat Struct Biol. 1998 Jun;5(6):427-31. PMID:9628478

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