4fv6
From Proteopedia
(Difference between revisions)
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<StructureSection load='4fv6' size='340' side='right' caption='[[4fv6]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4fv6' size='340' side='right' caption='[[4fv6]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4fv6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4fv6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FV6 FirstGlance]. <br> |
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E57:N-[(1S)-1-(3-CHLOROPHENYL)-2-HYDROXYETHYL]-4-(2-{[(2S)-1-HYDROXYBUTAN-2-YL]AMINO}-5-METHYLPYRIMIDIN-4-YL)-1H-PYRROLE-2-CARBOXAMIDE'>E57</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br> | </td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E57:N-[(1S)-1-(3-CHLOROPHENYL)-2-HYDROXYETHYL]-4-(2-{[(2S)-1-HYDROXYBUTAN-2-YL]AMINO}-5-METHYLPYRIMIDIN-4-YL)-1H-PYRROLE-2-CARBOXAMIDE'>E57</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fux|4fux]], [[4fuy|4fuy]], [[4fv0|4fv0]], [[4fv1|4fv1]], [[4fv2|4fv2]], [[4fv3|4fv3]], [[4fv4|4fv4]], [[4fv5|4fv5]], [[4fv7|4fv7]], [[4fv8|4fv8]], [[4fv9|4fv9]]</td></tr> | <tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fux|4fux]], [[4fuy|4fuy]], [[4fv0|4fv0]], [[4fv1|4fv1]], [[4fv2|4fv2]], [[4fv3|4fv3]], [[4fv4|4fv4]], [[4fv5|4fv5]], [[4fv7|4fv7]], [[4fv8|4fv8]], [[4fv9|4fv9]]</td></tr> | ||
| - | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERK2, MAPK1, PRKM1, PRKM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | + | <tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ERK2, MAPK1, PRKM1, PRKM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | <tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fv6 RCSB], [http://www.ebi.ac.uk/pdbsum/4fv6 PDBsum]</span></td></tr> | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fv6 RCSB], [http://www.ebi.ac.uk/pdbsum/4fv6 PDBsum]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
[[Category: Kang, Y N.]] | [[Category: Kang, Y N.]] | ||
[[Category: Stuckey, J A.]] | [[Category: Stuckey, J A.]] | ||
| - | [[Category: | + | [[Category: Xie, X.]] |
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 06:44, 24 September 2014
Crystal Structure of the ERK2 complexed with E57
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