Dethiobiotin synthetase
From Proteopedia
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | |||
| + | ===DTBS=== | ||
[[1dbs]], [[1dts]], [[1byi]] – EcDTBS – ''Escherichia coli''<br /> | [[1dbs]], [[1dts]], [[1byi]] – EcDTBS – ''Escherichia coli''<br /> | ||
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[[3of5]] – DTBS – ''Francicella tularensis'' | [[3of5]] – DTBS – ''Francicella tularensis'' | ||
| - | + | ===DTBS binary complex=== | |
[[3fmf]] – MtDTBS + DAN<br /> | [[3fmf]] – MtDTBS + DAN<br /> | ||
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[[1dai]] - EcDTBS + DAN | [[1dai]] - EcDTBS + DAN | ||
| - | + | ===DTBS ternary complex=== | |
[[3qxc]] - HpDTBS + Mg + ATP<BR /> | [[3qxc]] - HpDTBS + Mg + ATP<BR /> | ||
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[[3qxs]] - HpDTBS + Mg + phosphoaminophosphonic acid | [[3qxs]] - HpDTBS + Mg + phosphoaminophosphonic acid | ||
| - | + | ===DTBS quaternary complex=== | |
[[1dah]] - EcDTBS + DAN + Mn + ATP derivative<br /> | [[1dah]] - EcDTBS + DAN + Mn + ATP derivative<br /> | ||
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[[3qy0]] - HpDTBS + Mg + phosphate + GDP<BR /> | [[3qy0]] - HpDTBS + Mg + phosphate + GDP<BR /> | ||
| - | + | ===DTBS higher complexes=== | |
[[1dam]] - EcDTBS + DTB + Mg + phosphate + ADP<BR /> | [[1dam]] - EcDTBS + DTB + Mg + phosphate + ADP<BR /> | ||
Revision as of 10:24, 17 August 2014
Template:STRUCTURE 1bs1
Dethiobiotin synthetase (DTBS) catalyzes the first ring closure in the biotin synthesis. The reaction transforms 7,8-diaminononanoate (DAN), ATP and CO2 to dethiobiotin (DTB), ADP and phosphate.
Contents |
3D dethiobiotin synthetase
Updated on 17-August-2014
DTBS
1dbs, 1dts, 1byi – EcDTBS – Escherichia coli
2qmo – HpDTBS – Helicobacter pylori
3fgn – MtDTBS – Mycobacterium tuberculosis
3of5 – DTBS – Francicella tularensis
DTBS binary complex
3fmf – MtDTBS + DAN
1dad – EcDTBS + ADP
1dae - EcDTBS + nonanedioate derivative
3fmi – MtDTBS + aminopelargonic acid
1dai - EcDTBS + DAN
DTBS ternary complex
3qxc - HpDTBS + Mg + ATP
1daf - EcDTBS + DAN + ADP
1dag - EcDTBS + DAN + ATP derivative
3qxj - HpDTBS + Mg + ATP
3qxs - HpDTBS + Mg + phosphoaminophosphonic acid
DTBS quaternary complex
1dah - EcDTBS + DAN + Mn + ATP derivative
1bs1 - EcDTBS + DTB + Mg + ADP
1a82 - EcDTBS + DAN + Mg + ATP
3fpa - MtDTBS + DTB + Mg + phosphate
3mle - HpDTBS + Mg + phosphate + ADP
3qy0 - HpDTBS + Mg + phosphate + GDP
DTBS higher complexes
1dam - EcDTBS + DTB + Mg + phosphate + ADP
1dak - EcDTBS + DAN + mixed anhydride + Mg + phosphate + ADP
3qxh - HpDTBS + aminooctanoic acid + Mg + phosphate + ADP
3qxx - HpDTBS + aminooctanoic acid + Mg + phosphate + GTP
