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4eax

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4eax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EAX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4eax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EAX FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S12:O-[(S)-HYDROXY{[(2S)-2-HYDROXY-3-(OCTADEC-9-ENOYLOXY)PROPYL]OXY}PHOSPHORYL]-L-SERINE'>S12</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S12:O-[(S)-HYDROXY{[(2S)-2-HYDROXY-3-(OCTADEC-9-ENOYLOXY)PROPYL]OXY}PHOSPHORYL]-L-SERINE'>S12</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eax RCSB], [http://www.ebi.ac.uk/pdbsum/4eax PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eax RCSB], [http://www.ebi.ac.uk/pdbsum/4eax PDBsum]</span></td></tr>
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<table>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE]] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Jiang, T.]]
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[[Category: Jiang, T]]
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[[Category: Tong, Q.]]
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[[Category: Tong, Q]]
[[Category: Hormone]]
[[Category: Hormone]]
[[Category: Lyso-p]]
[[Category: Lyso-p]]
[[Category: Phospholipid]]
[[Category: Phospholipid]]

Revision as of 16:49, 25 December 2014

Mouse NGF in complex with Lyso-PS

4eax, resolution 2.30Å

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